Results 131 to 140 of about 39,328,094 (290)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Open research data: Report to the Australian National Data Service (ANDS) [PDF]
, 2014 Main points Research data are an asset we have been building for decades, through billions of dollars of public investment in research annually. The information and communication technology (ICT) revolution presents an unprecedented opportunity to ...
Nicholas Gruen, John Houghton
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
, 2020 Open Data for Development (OD4D) is the leading global partnership created to advance open data innovation and use around the world. This annual report provides an overview on the global context, trends, and issues influencing the program, and summarizes
Open Data for Development Network
core +1 more source
Using mixed methods to track the growth of the Web: tracing open government data initiatives
, 2012 In recent years, there have been a rising number of Open Government Data (OGD) initiatives; a political, social and technical movement armed with a common goal of publishing government data in open, re-usable formats in order to improve citizen-to ...
Carr, Leslie +3 more
core +1 more source
Investigating privacy risks in open government data: an exploratory case study
Information Research: An International Electronic JournalIntroduction. As governments increasingly release large datasets to the public, concerns have arisen regarding the potential risks associated with the inadvertent disclosure of personal information.
Daniel Carter, Caroline Stratton
doaj +1 more source
Open government data portals in the European Union: A dataset from 2015 to 2017. [PDF]
Data Brief, 2020 de Juana-Espinosa S, Luján-Mora S.
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source