Results 141 to 150 of about 39,328,094 (290)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
, 2015 A conference panel discussing artists' use of Open Data with Hannah Redler (curator at Open Data Institute, London), Thomson & Craighead (ODI artists in residence), Julie Freeman (artist) and Jonathan Reekie (Director, Somerset House ...
Craighead, A., Thomson, J.
core
Improving Indonesia's Commitment to Open Government Through Online Petition
, 2019 Since 2011 Indonesia has joined as a member of Open Government Partnership, which is an international platform for countries committed to making their government more open, accountable, and responsive to citizens.
Kusumaningrum, Adi; Brawijaya University +2 more
core +1 more source
DIPIM model: Comprehensive Process for Opening Public Data
ManagementResearch Question: This paper investigates which concrete steps are essential for opening data in public institutions to ensure comprehensiveness, adaptability and sustainability of the process.
Tea Borozan +2 more
doaj +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Open data barometer global report [PDF]
, 2015 Highlights the lack of open and accessible data on the performance of key public services. If the political and social impacts of open data are to be realised, work to increase the supply of datasets from right across government will be needed, alongside
World Wide Web Foundation
core
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
The Generative Mechanisms Of Open Government Data. [PDF]
, 2013 The exponentially growing production of data enables global connectivity as well as increased openness and sharing, which turn into a powerful force that is changing the global economy and society. Governments around the world have become active participants in this evolution by opening up their data for access and re-use by public and private agents ...
Jetzek, Thorhildur +2 more
openaire +2 more sources