Results 121 to 130 of about 636,394 (303)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Open data barometer global report [PDF]

open access: yes, 2015
Highlights the lack of open and accessible data on the performance of key public services. If the political and social impacts of open data are to be realised, work to increase the supply of datasets from right across government will be needed, alongside
World Wide Web Foundation
core  

Scientometric Analysis of Political Documents of Overton: Open Government Data Case Study [PDF]

open access: yesمجله علم‌سنجی کاسپین
Background and aim: Open Government Data is essential for today's civil society. The aim of this article is scientometric analysis of political documents based on open government data in Overton database.
Forough Rahimi, Farshid Danesh
doaj  

Open government data and entrepreneurship: Evidence from China

open access: yesInternational Review of Economics & Finance
Using the establishment of open government data platforms as a quasi-natural experiment, we employ the staggered difference-in-differences model to identify the causal impact of open government data on entrepreneurship.
Jinlei Li, Lei Wang, Yuanbiao Huang
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The Importance of Authoritative URI Design Schemes for Open Government Data

open access: yes, 2015
A major challenge when working with open government data is managing, connecting, and understanding the links between references to entities found across multiple datasets when these datasets use different vocabularies to refer to identical entities (i.e.
Hendler, James A.   +3 more
core  

How Open Government Data Enhances Public Service Delivery: A Quasi-Natural Experiment from Government Data Platforms

open access: yesSystems
Enhancing the level of public service delivery constitutes a core objective for governments worldwide in their efforts to optimize governance effectiveness.
Yuhui Guo, Zexun Zhang
doaj   +1 more source

Optimizing the Retrieval of the Vital Status of Cancer Patients for Health Data Warehouses by Using Open Government Data in France. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Lauzanne O   +5 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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