Results 101 to 110 of about 777,087 (303)

Funding Open Data [PDF]

open access: yes, 2018
Open government data are fast becoming entrenched in our society. However, even though open government data may be “free”, it is not “gratis”. It takes substantial human and financial resources not only to collect and maintain government data, but also ...
Welle Donker, F.M. (author)   +1 more
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Breaking Public Administrations' Data Silos: the Case of Open-DAI, and a Comparison between Open Data Platforms [PDF]

open access: yes, 2014
An open reuse of public data and tools can turn the government into a powerful ‘platform' also involving external innovators. However, the typical information system of a public agency is not open by design.
Morando, Federico   +4 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The Value Generating Mechanisms of Open Government Data

open access: yesGeoforum Perspektiv, 2013
Recent trends towards openness and technical connectivity have offered the ability to drive massive social and economic change; however they demand a redefinition of relationships. We have observed a move from a polarized world where companies operate in
Thorhildur Jetzek
doaj   +1 more source

Open Government Data: A Stage Model [PDF]

open access: yes, 2011
Public sector information constitutes a valuable primary material for added-value services and products, which however remains unexploited. Recently, Open Government Data (OGD) initiatives emerged worldwide aiming to make public data freely available to everyone, without limiting restrictions.
Evangelos Kalampokis   +2 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Open research data: Report to the Australian National Data Service (ANDS) [PDF]

open access: yes, 2014
Main points Research data are an asset we have been building for decades, through billions of dollars of public investment in research annually. The information and communication technology (ICT) revolution presents an unprecedented opportunity to ...
Nicholas Gruen, John Houghton
core  

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