Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Making Sense of Open Government Data
Data.gov, a major distributor of raw US government data, has published thousands of raw datasets on the Web for public access. While these datasets provide useful information, their potential has not yet been fully realized due to usability-related ...
Hendler, James A. +3 more
core
Comparative analysis of open government data topics and usability. [PDF]
Cho J.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Linked Open Government Data: Still a Viable Option for Sharing and Integrating Public Data?
Linked Data (LD) principles, when applied to Open Government Data (OGD), aim to make government data accessible and interconnected, unlocking its full potential and facilitating widespread reuse.
Alfonso Quarati, Riccardo Albertoni
doaj +1 more source
Roadblocks Hindering the Reuse of Open Geodata in Colombia and Spain: A Data User’s Perspective
Open data initiatives are playing an important role in current city governments. Despite more data being made open, few studies have looked into barriers to open geographic data reuse from a data consumer’s perspective.
Fernando Benitez-Paez +3 more
doaj +1 more source
Open government data: A systematic literature review of empirical research. [PDF]
Wirtz BW +3 more
europepmc +1 more source
From open government to open government data: a bibliometric view
Vanessa Hernandes Oliveira d +3 more
openaire +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source

