Results 111 to 120 of about 636,394 (303)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

TWC LOGD: A Portal for Linked Open Government Data Ecosystems

, 2011
pages 1 - 11International open government initiatives are releasing an increasing volume of raw government datasets directly to citizens via the Web. The transparency resulting from these releases creates new application opportunities but also imposes ...
Flores, Johanna, Williams, Gregory, Hendler, James A., Michaelis, James, Li, Xian, Erickson, John S., Graves, Alvaro, Zheng, Jin, DiFranzo, Dominic, Ding, Li, McGuinness, Deborah L., Lebo, Tim   +11 more
core  

Integrated statistical indicators from Scottish linked open government data. [PDF]

Data Brief, 2023
Karamanou A, Kalampokis E, Tarabanis K.
europepmc   +1 more source

From open government to open government data: a bibliometric view

Electronic Government, an International Journal, 2023
Vanessa Hernandes Oliveira d, e Oliveira, Paulo Gonçalves Pinheiro, Nelson Guilherme Machado Pinto   +3 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Open data and charities

, 2012
Open data involves a paradigm shift in the way organisations manage their information and data: moving from a default of charities keeping data resources locked up in underused internal systems, to building a shared ‘Web of Data’.
Tiropanis, Thanassis, Hall, Wendy, O'Hara, Kieron, Shadbolt, Nigel, Davies, Tim   +4 more
core  

Open Government Data Topic Modeling and Taxonomy Development

Systems
The expectations for the (re)use of open government data (OGD) are high. However, measuring their impact remains challenging, as their effects are not solely economic but also long-term and spread across multiple domains.
Aljaž Ferencek, Mirjana Kljajić Borštnar   +1 more
doaj   +1 more source

Exploring the Quality of Dynamic Open Government Data Using Statistical and Machine Learning Methods. [PDF]

Sensors (Basel), 2022
Karamanou A, Brimos P, Kalampokis E, Tarabanis K.   +3 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Privacy and Open Government

Future Internet, 2014
The public-oriented goals of the open government movement promise increased transparency and accountability of governments, enhanced citizen engagement and participation, improved service delivery, economic development and the stimulation of innovation ...
Teresa Scassa
doaj   +1 more source