Results 101 to 110 of about 609,082 (292)
Exposure to green areas: modelling health benefits in a context of study heterogeneity [PDF]
, 2019 This is the final version. Available on open access from Elsevier via the DOI in this record Although the beneficial health effects of green areas are gaining recognition, epidemiological studies show mixed results with significance varying considerably ...
Suárez Gálvez, Cristina Isabel +20 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Evaluasi Ruang Terbuka Hijau di Kota Pekanbaru
Planta Tropika: Jurnal Agrosains, 2015 The research was conducted to evaluate the availability of open green area in Pekanbaru and to make the landscape model of green open area. This evaluation was needed to improve the functional and aesthetic value of green open area in Pakanbaru.
Lis Noer Aini +2 more
doaj
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
New Urban Governance in Controlling Public Green Open Spaces in Indonesia [PDF]
E3S Web of ConferencesThis study aims to describe how new urban governance controls public green open spaces in Indonesia. Cities in Indonesia experience an imbalance of public green open space that must be provided.
Sulistyaningsih Tri, Sunarto, Kulsum Umi
doaj +1 more source
Open and green areas Soma (Manisa) district determining potential
, 2010 Fen Bilimleri Enstitüsü, Peyzaj Mimarlığı Ana Bilim DalıHızlı kentleşme, sanayileşme ve artan nüfus, mekânlarda yapılaşmaların artmasına, açık-yeşil alanların miktarının giderek azalmasına neden olmakta ve bunun sonucu kentli doğadan hızla kopmaktadır ...
Günal, İlknur
core
, 2019 This paper studies the size and location of urban green areas across city spaces. Urban green areas offer amenities that affect residential choices, land consumption and land rent.
TRAN, Thi Thu Huyen, PICARD, Pierre M
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
THE CONCEPTS ON QUALITY OF LIFE IN THE MARIBOR POST-WW2 HOUSING ESTATES [PDF]
AR: Arhitektura, Raziskave, 2012 The paradigm of quality of life in housing depends on variousinterconnectedness functions, which satisfy not only the needsof dwellers but also the inhabitants of the city, in general.
Vanja Skalicky, Metka Sitar
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source