Results 121 to 130 of about 609,082 (292)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
A research carried out to determine the open and green areas of Çorlu in Tekirdağ province
, 2007 Yüksek lisans teziAraştırma alanı olan Çorlu ilçesi, sanayinin etkisi ile çok kısa bir zamanda büyük bir yapı kitlesi haline gelmiştir. Bunun sonucu açık ve yeşil alan sistemi yeterli bir gelişim gösterememiştir.
Tosun, Erkan
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Open Green Area Strategies and Action Planning in Resilient Coastal Cities
Black Sea Journal of Engineering and ScienceCities, as complex entities composed of interdependent and multi-layered systems, are inherently vulnerable to both natural disasters and human-induced threats. Nevertheless, they are not only spaces exposed to adverse impacts but also strategic hubs for infrastructure, sustainability, technology, and investment.
Merve Sipahi, Şevval Bozkurt
openaire +1 more source
A Welfare Evaluation of Green Urban Areas
, 2020 Urban green areas cover more than 6% of urban land in Europe. This paper quan-tifies the impact of urban green areas on city structures for more than 300 Europeancities.
PICARD, Pierre M, Tran, Huyen
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Evaluation Open and Green Areas of Kayseri Urban Complex with a System Approach
Selçuk Üniversitesi Mühendislik, Bilim ve Teknoloji Dergisi, 2005 In urban environments green areas play an important part in forming good qualityenvironments with their ecological, economical, physical, social and aesthetic functions. Open and greenarea systems contribute the formation of urban communities by creating more livable environments. Inthis reseearch open and green areas have been searched in the frame of
KURTASLAN, Banu Öztürk +1 more
openaire +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
THE CONCEPT OF GREEN HOME IN HOUSING AREAS (FUTURE OPPORTUNITY AND CHALLENGE) [PDF]
, 2008 The concept of green home is a part of green architecture having the objective of harmonizing the inhabitants and the environment. In the context of real estate housing areas, various housing products having natural themes, such as, green city, green ...
Purwanto, Edi
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