Results 131 to 140 of about 609,082 (292)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
How Do Homebuyers Value Different Types of Green Space?
It is important to understand tradeoffs in preferences for natural and constructed green space in semi-arid urban areas because these lands compete for scarce water resources.
Osgood, Daniel E. +3 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
, 2020 In recent years, rapid population growth and urbanization that have grown in parallel with industrialization have caused cities to develop on natural areas. This development has brought about changes in natural areas and ecological cycle.
Koçan, Nurhan
core +1 more source
Needs analysis for public green spaces in Grosuplje [PDF]
Urbani Izziv, 2008 A huge increase in residential and business-commercial construction has characterised Grosuplje, a young town and suburban settlement of the greater Ljubljana area, over the last two decades, thereby increasing the number of possible users of its open ...
Klara Sulič, Ana Kučan
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The effect of urban open green areas on carbon footprint
Urban open green areas are the most important component of urban planning. A city's ability to live in a philosophy that is compatible with ecological principles and takes into account natural processes depends on the correct planning of open green areas.
Demiroğlu, Demet +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Ciência Florestal, 2011 The importance of the green areas is increasing since they are an important factor in the health and welfare of urban population. Therefore, in Parral city, in Central Chile, it was quantified and analyzed the availability of green areas and vegetation ...
Carlos Mena +4 more
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