Results 31 to 40 of about 2,286,604 (339)

Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment

Nature Communications, 2020
AnnexinV has been shown to bind phosphatidylserine expressed by chemotherapy-induced apoptotic cells increasing their immunogeneicity. Here, the authors demonstrate in a preclinical tumor model that fusing tumor-antigen peptide to Annexin V enhances its ...
Tae Heung Kang, Jung Hwa Park, Andrew Yang, Hyun Jin Park, Sung Eun Lee, Young Seob Kim, Gun-Young Jang, Emily Farmer, Brandon Lam, Yeong-Min Park, Chien-Fu Hung   +10 more
doaj   +1 more source

TMT diversity and innovation ambidexterity in family firms [PDF]

, 2019
Purpose – Family firms that simultaneously engage in multiple levels of innovation – incremental andradical – are likely to enjoy performance advantages across generations.
Röd, Irina
core   +1 more source

Examining iPSC derived motor neuron variability and genome stability monitoring as a solution

Scientific Reports
Induced pluripotent stem cell (iPSC)-derived motor neurons (MNs) offer a promising model system for understanding motor neuron diseases (MNDs) and advancing drug discovery.
Finbar Gaffey, David McCoull, Egle Vaitone, Erin Hedges, Christopher Lovejoy, Zhi Yao, Paul D. Wright, Richard J. Mead, Will Stebbeds   +8 more
doaj   +1 more source

PRUAB Innoget Cloud, nova plataforma de gestió d'oferta i demanda tecnològica [PDF]

, 2013
El Parc de Recerca UAB ha posat en marxa aquesta eina tecnològica que permet fomentar i estructurar les col·laboracions en R+D+i entre els més de 4.000 investigadors vinculats al Parc i empreses de la B30, nacionals i internacionals. D'aquesta manera, es
Open Innovation Marketplace
core   +1 more source

Incidence and Outcome of Infants With Cancer in Canada: A Report From Cancer in Young People in Canada Database

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Infants with cancer are rare and face unique challenges. Our study aims to describe the incidence of infantile cancers in Canada and to compare treatment‐related mortality (TRM) and their outcomes with those of older children. Methods We conducted a retrospective cohort study using the Cancer in Young People in Canada database ...
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Sylvia Cheng, Lesleigh Abbott, Tony Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Donna L. Johnston, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +22 more
wiley   +1 more source

Open Innovation, ambiguity and technological convergence [PDF]

, 2017
Objectives. Current paper aims to provide a fresh conceptual framework on the relationship among open innovation, decision ambiguity, and technological convergence.
Ferri, M. A., Orlando, B., Renzi, A., Sancetta, G.   +3 more
core  

What to Do When Medical Evidence Can Only Be Generated Through Routine Data: An Example From Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt, Antje Walz, Dietrich Knoerzer   +2 more
wiley   +1 more source

Cross-modal adaptive reconstruction of open education resources

Scientific Reports
Matching vast online resources to individual learners’ needs remains a major challenge, especially for adults with diverse backgrounds. To address this challenge, we proposed a Dynamic Knowledge Graph-enhanced Cross-Modal Recommendation model (DKG-CMR ...
Tang Shengju, Feng Li, Zhan Wang, Xie Zhaoyuan   +3 more
doaj   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

Collective Innovation in Open Source Hardware

, 2014
A growing community that shares digital 3D designs has created an opportunity to study, encourage and stimulate innovation. This remix community allows people not only to prototype at a minimal cost but also to work on projects they are genuinely ...
Kyriakou, Harris, Nickerson, Jeffrey V.
core   +1 more source