Results 51 to 60 of about 391,323 (294)

Predicting students’ academic progress and related attributes in first-year medical students: an analysis with artificial neural networks and Naïve Bayes

BMC Medical Education
Background Dropout and poor academic performance are persistent problems in medical schools in emerging economies. Identifying at-risk students early and knowing the factors that contribute to their success would be useful for designing educational ...
Diego Monteverde-Suárez, Patricia González-Flores, Roberto Santos-Solórzano, Manuel García-Minjares, Irma Zavala-Sierra, Verónica Luna de la Luz, Melchor Sánchez-Mendiola   +6 more
doaj   +1 more source

Maneuvering the bumps in the New Silk Road: Open innovation, technological complexity, dominant design, and the international impact of Chinese innovation [PDF]

, 2021
Alexander Brem, Petra A. Nylund
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Evaluation of the redox alteration in Duchenne muscular dystrophy model mice using in vivo DNP-MRI

npj Imaging
Duchenne muscular dystrophy (DMD) is a genetic muscular disease and is the most common type of muscular dystrophy in Japan. Noninvasive magnetic resonance imaging (MRI) can be used for follow-up evaluation of myositis and muscular dystrophy, including ...
Hinako Eto, Masaharu Murata, Takahito Kawano, Yoko Tachibana, Abdelazim Elsayed Elhelaly, Yoshifumi Noda, Hiroki Kato, Masayuki Matsuo, Fuminori Hyodo   +8 more
doaj   +1 more source

Multi-sided platforms as catalysts for responsible innovation in healthcare: Patient Innovation as a case-study

Journal of Responsible Innovation
Healthcare systems face increasing pressure from aging populations, chronic diseases, and the demand for accessible, high-quality care. Yet many innovations fail to address the needs of vulnerable groups.
Gemma Tria, Maria João Jacinto, Margarida Oliveira, Helena Canhão, Pedro Oliveira   +4 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Managing Strategic Changes in Personnel Resistance to Open Innovation in Companies [PDF]

, 2022
Oleksandr Bіlichenko, Mikhail Tolmachev, Т. В. Полозова, Dmytro Aniskevych, Alzoubi Laith Abdel Karim Mohammad   +4 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Developing a framework for measuring open innovation in defense industry [PDF]

بهبود مدیریت, 2019
Evidence in defense industry including knowledge dispersion and budget cuts demonstrate increasingly necessity of moving toward open innovation as defense industry in united states of America, England, and many other countries are opening their ...
Ebrahim Sozanchi Kashani, Hossein Arjini, Mehdi Moghayadnia   +2 more
doaj  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source