Results 51 to 60 of about 1,564,341 (308)

Open innovation: the missing nexus between entrepreneurial orientation, total quality management, and performance of SMEs

open access: yesJournal of Innovation and Entrepreneurship, 2023
Drawing upon the theoretical foundations of the resource-based view, the current research aims to examine the mediating role of open innovation between entrepreneurial orientation, total quality management, and SMEs performance.
Muzaffar Asad   +4 more
doaj   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian   +7 more
wiley   +1 more source

Open Innovation neu denken und steuern: Ein Beitrag aus der Perspektive des Innovationsmanagements an der ETH-Bibliothek

open access: yes027.7, 2015
Der Artikel nennt und erläutert Grundlagen und exemplarische Felder, die sich aus Sicht des Innovationsmanagements an der ETH-Bibliothek anbieten, um Open Innovation zu implementieren und etablierte Methoden des Innovationsmanagements zu erweitern ...
Franziska Regner
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Open Innovation in Organization Through Stakeholder Capability During Pandemic (COVID-19): Indonesian SMEs Perspective

open access: yesIEEE Access, 2022
This study aims to analyze the role of stakeholders who support the open innovation transition in SMEs. This is important because the innovation process has shifted from closed innovation to open innovation which requires good management of ...
Augustina Asih Rumanti   +3 more
doaj   +1 more source

A case study in open source innovation: developing the Tidepool Platform for interoperability in type 1 diabetes management. [PDF]

open access: yes, 2015
OBJECTIVE:Develop a device-agnostic cloud platform to host diabetes device data and catalyze an ecosystem of software innovation for type 1 diabetes (T1D) management.
Adi, Saleh   +8 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Whole brain gray matter volume may mediate the relationship between light physical activity and Body Mass Index in middle-aged Japanese adults

open access: yesBrain Research Bulletin
Obesity is a multifactorial condition that cannot be fully explained by traditional energy-balance models. Recent studies highlight the role of brain structure—particularly gray matter volume—as a potential risk factor of obesity.
Juan Cesar D. Pineda   +2 more
doaj   +1 more source

Thought for Food: the impact of ICT on agribusiness [PDF]

open access: yes, 2009
This report outlines the impact of ICT on the food economy. On the basis of a literature review from four disciplines - knowledge management, management information systems, operations research and logistics, and economics - the demand for new ICT ...
Bunte, F.H.J.   +6 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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