Results 61 to 70 of about 1,564,341 (308)

Opening the black box: How staff training and development may affect the innovation of enterprises [PDF]

, 2010
We describe a research on the interplay that appears to exist in companies between Human Resource Management and innovation. This complex, multicomponent, non-linear and dynamic interplay is often viewed as a "black box".
Brassesco, Barbara, Brizio, Adelina, Carpaneto, Alberto, Mate, Davide, Rabellino, Daniela, Rezzonico, Raffaele, Surra, Fabio, Tirassa, Corrado, Tirassa, Maurizio   +8 more
core  

Conceptualizing the innovation process towards the ‘active innovation paradigm’—trends and outlook [PDF]

, 2016
This paper introduces the evolving understanding and conceptualization of innovation process models. We categorize the different approaches to understand and model innovation processes into two types.
Dirk Meissner, Maxim Kotsemir
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Continuous inhalation of essential oil increases gray matter volume

Brain Research Bulletin
Research into the health benefits of scents is on the rise. However, little is known about the effects of continuous inhalation, such as wearing scents on clothing, on brain structure.
Keisuke Kokubun, Kiyotaka Nemoto, Yoshinori Yamakawa   +2 more
doaj   +1 more source

Affiliated Participation in Open Source Communities [PDF]

, 2019
Background: The adoption of Free/Libre and Open Source Software (FOSS) by institutions is significantly increasing, and so is the affiliated participation (the participation of industry engineers in open source communities as part of their jobs).
Alami, Adam, Wasowski, Andrzej
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

The brain that understands different cultures: MRI-measured brain structure correlates with cultural intelligence

Acta Psychologica
In today's world of increasing globalization, the importance of cultural intelligence (CQ), a necessary capability for cross-cultural adaptation, is becoming more and more recognized.
Keisuke Kokubun, Kiyotaka Nemoto, Yoshinori Yamakawa   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Open innovation: A preliminary model from the Knowledge-based Theory

Intangible Capital, 2011
Purpose: The open innovation paradigm is an alternative and/or complementary way to knowledge management processes in its various stages, questioning the basic assumptions where some of the technological innovation strategies and processes are based on ...
Rocío González-Sánchez, Fernando E. García-Muiña   +1 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source