Results 131 to 140 of about 40,814,819 (270)

Using open accessibility data for accessible travelling

, 2014
This paper summarizes the research of using open accessibility data for accessible travelling. With the aim of addressing the gap between users’ special needs and complex accessibility barriers in real world, we proposed a personalized accessible ...
Ding, Chaohai, Wald, Mike, Wills, Gary
core   +1 more source

Linked open data and research knowledge management : an exploratory search and visualization framework

, 2014
This paper describes and evaluates an exploratory search and visualization framework that enables non-expert users to interact and intuitively explore academic and bibliographic information. The framework, called the ‘Linked Open Data Visualizations Suite’ (LOD/VizSuite), uses the Linked Open Data (LOD) of RILOD, a database with academic bibliographic ...
Mechant, Peter, Van Compernolle, Mathias, Dimou, Anastasia, De Vocht, Laurens, De Marez, Lieven   +4 more
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Leveraging the Saudi Linked Open Government Data: A Framework and Potential Benefits [PDF]

International Journal of Modern Education and Computer Science, 2019
Afnan M. AlSukhayri, Muhammad Ahtisham Aslam, Sachi Arafat, Naif Radi Aljohani   +3 more
openaire   +1 more source

A Novel Framework to Describe Technical Accessibility of Open Data

, 2015
Open Data is a recent and important movement that has economic, social, and political benefits. Despite a lot of attention in literature there are still limitations with the existing Open Data frameworks in describing technical accessibility of Open Data.
Faichney, Jolon, Stantic, Bela
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

An Honest Broker System for Secure Linkage of Opioid-related Clinical, Prescription, and Outcomes Data. [PDF]

Anesthesiol Open
Stathakios J, Brummett CM, Gunaseelan V, Kaleba EO, Waljee JF, Bicket MC.   +5 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

From Data Poverty to Data Sovereignty: Operationalizing Gold-Standard Biomedical Datasets in Low- and Middle-Income Countries. [PDF]

JMIR Med Inform
Rana S, Bhagat P, Pal D, Pati S, Singh H.   +4 more
europepmc   +1 more source