Results 121 to 130 of about 8,213,046 (356)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Jointing design in open plan system for office [PDF]

, 2008
Most modern offices use open plan office system due to the flexibility of the product. The open plan system (OPS) can be customized from low screen to high screen and can be installed and dismantled according to the office needs.
Abdul Rahman, Ahmad Rizal, Dolah, Mohd Shahrizal, Mohd Yusuff, Rosnah, Osman, Mohd Rasid   +3 more
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

How to enhance student satisfaction in Chinese open education? A serial multiple mediating model based on academic buoyancy and flow experience

Acta Psychologica
With the rapid development of information technology and the widespread acceptance of the concept of sharing educational resources, open education has gradually become an important part of China's national education system as a flexible and efficient ...
Yulin Lu, Feng Li, Chao Gao, Xiaoli Zhu, Lijun Lian   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

PRS Global Open: A Dream Turning to Reality

Plastic and Reconstructive Surgery, Global Open, 2020
Rod J. Rohrich, MD, Aaron G. Weinstein, MS, Isiah Donnell Moore, BA, James M. Stuzin, MD   +3 more
doaj   +1 more source

Sickness absence associated with shared and open-plan offices – a national cross sectional questionnaire survey

Scandinavian Journal of Work, Environment & Health, 2011
OBJECTIVE: The aim of this study was to examine whether shared and open-plan offices are associated with more days of sickness absence than cellular offices.
Jan H Pejtersen, Helene Feveile, Karl Bang Christensen, Hermann Burr   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

STREAM Journal, Vol. 1, No. 3, pp 1-16. July-September 2002 [PDF]

, 2002
CONTENTS: From resource user to resource manager: a significant change story, by Ruperto Aleroza as told to Jocel Pangilinan and Ronet Santos. Significant change with Cambodian provincial livelihoods study teams, by Bun Hay Chheng, Tan Someth Bunwhat ...

core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source