Results 71 to 80 of about 779,176 (309)

Open-office Noise ICT-5

open access: yes, 2023
The aim of this between subjects experiment is to investigate whether open office noise affects information processing. It is hypothesized that open office noise has a negative effect on information processing.
Fleur Petit   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

AVAILABILITY AND UTILIZATION OF E-COUNSELLING PLATFORMS FOR QUALITY DISTANCE LEARNING IN NATIONAL OPEN UNIVERSITY OF NIGERIA

open access: yesIndonesian Journal of Learning and Instruction, 2018
The emergence of technology has made it possible for counsellors all over the world to reach their clients in distant locations without compromising the principle of confidentiality.
Augustine C. Ukwueze
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Measurement model of readiness for online testing of undergraduate students in Thailand’s distance education programs [PDF]

open access: yesAAOU Journal
Purpose – This study aims to develop a model for readiness measurement and to study readiness levels for online testing of undergraduate students in Thailand’s distance education programs.
Thanyasinee Laosum
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

News from the Office of Research

open access: yes, 2016
September 1, 2016: September research workshops -- Deadline for WSU research grants is Oct.7 -- Intellectual property management workshop -- WSU announces request for proposals for interdisciplinary cluster hire -- T3 moves to Research and Technology ...
Office of Research
core  

Good (Digital) Research Practice and Open Science Support and Best Practices for Implementing the DFG Code of Conduct “Guidelines for Safeguarding Good Research Practice”. Helmholtz Open Science Briefing. Good (Digital) Research Practice and Open Science Support and Best Practices for Implementing the DFG Code of Conduct “Guidelines for Safeguarding Good Research Practice” Version 2.0

open access: yes, 2022
The German Research Foundation’s (DFG) Code of Conduct “Guidelines for Safeguarding Good Research Practice” has been in force since August 1, 2019. Open science aspects are of relevance to many of the guidelines contained in the Code.
Messerschmidt, Reinhard   +7 more
core   +1 more source

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