Results 91 to 100 of about 20,084,391 (297)
Does the use of standing 'hot' desks change sedentary work time in an open plan office?
, 2012 Objective: This study assessed the use of standing 'hot' desks in an open plan office and their impact on sedentary work ...
Gilson, Nicholas D. +13 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A knowledge graph and contrastive learning framework for evaluating digital economy development
Discover Artificial IntelligenceThis study proposes a digital economic development evaluation algorithm that integrates knowledge graphs and contrastive learning. By constructing a digital economic knowledge graph containing 120,000 entities and 650,000 relationships, the ...
Chengxia Li
doaj +1 more source
Big Earth DataData visualization is a key component of any scientific data analysis workflow and is vital for the summarization and dissemination of complex ideas and results.
William Gearty
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Enhancing Student Engagement Prediction in Online Education Through Deep Learning
Journal of Applied Science and EngineeringThe rapid growth of online learning platforms has transformed education by enabling students to access learning resources anytime and anywhere. Despite these advantages, maintaining student engagement remains a significant challenge, as engagement ...
Xiaofang Qin
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Positive Effect of Non-territorial Office on Privacy
Annals of Business Administrative Science, 2013 The office research in environmental psychology that was inspired by the non-territorial office experiments of Allen and his colleagues in 1970, and undertaken since the 1980s, deemed privacy in the open office setting problematic; however, experiments ...
Nobuyuki INAMIZU
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source