Results 81 to 90 of about 779,176 (309)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

News from the Office of Research

, 2019
February 2019: National Institutes of Health (NIH) Reminder of Policy Changes for proposals -- URCA due April 5 -- Higuchi - KU Endowment Research Achievement Awards -- New policy regarding use of UAS on campus -- WSU team creates device that will aid in
Office of Research
core  

Exploring Workplace Mental Health and Counseling Needs in Open University Staff: A Mixed-Methods Study

Journal of Health Research
Background: Workplace mental health is a growing concern in higher education, especially in open and distance learning (ODL) settings, where staff face unique stressors.
Pathanin Sangaroon, Oranuch Kanjanaprakorn, Araya Prasertchai, Worrawit Nakpan   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Peranan ‘open office’ sambutan Aidilfitri mampu kukuhkan ikatan komuniti kampus [PDF]

Sambutan Hari Raya Aidilfitri menjadi tanda permulaan yang penuh dengan kegembiraan dan perpaduan. Di Malaysia, tradisi rumah terbuka atau 'open house' merupakan salah satu elemen khas yang menyerlahkan keramahan dan kebudayaan unik masyarakat tempatan ...
Ezihaslinda, Ngah, Zuraina, Ali
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

deeptime: an R package that facilitates highly customizable and reproducible visualizations of data over geological time intervals

Big Earth Data
Data visualization is a key component of any scientific data analysis workflow and is vital for the summarization and dissemination of complex ideas and results.
William Gearty
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Office soundscape assessment: A model of acoustic environment perception in open-plan offices [PDF]

The soundscape approach has been utilised in recent research for residential environments, but applications to indoor working environments remain limited.
Ali-MacLachlan, Islah, Deuchars, Angus, West, Benjamin   +2 more
core   +1 more source