Results 151 to 160 of about 2,192,791 (336)

Improving the Peer Review Process: A Proposed Market System [PDF]

open access: yes, 2016
The current peer review system suffers from two key problems: promotion of an in-crowd whose methods, opinions and innovations it protects; and failure to represent the opinions and interests of non-peer clients.
Frijters, Paul, Torgler, Benno
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Pushing Past the Paywall: Accessing Open Peer-Reviewed Research

open access: gold, 2023
Bryan G. Cook   +7 more
openalex   +1 more source

Open Access, Open Monographs, Open Data, Open Peer Review

open access: yeseLucidate, 2019
Last year’s UKeiG professional development programme was a huge success attracting delegates from all sectors and disciplines of the library and information profession. UKeiG Chair David Ball’s workshop – “Open Access, Open Monographs, Open Data, Open Peer Review” – provided food for thought and a state-of-the-art overview of the complex issues around ...
openaire   +1 more source

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