Results 131 to 140 of about 668,202 (287)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Open science publishing practices can break commercial publishers’ dominant position in the dissemination of scientific results

open access: yesDutch Journal of Applied Linguistics
In this response to Diamond is a scientist's best friend, Pascal Braak discusses open science practices from a bibliographic perspective and among other things, sketches how a fully open and transparent knowledge generation process may break the power ...
Pascal Braak
doaj   +1 more source

Encuesta sobre evaluación por pares y el módulo "Open Peer Review" de DIGITAL.CSIC

open access: yes, 2018
Imagen realizada para divulgar el "Informe de la encuesta sobre evaluación por pares y el módulo "Open Peer Review" de DIGITAL.CSIC".En febrero de 2018 la Oficina Técnica de DIGITAL.CSIC lanzó una nueva encuesta para los investigadores CSIC para analizar
Román-Molina, Juan
core   +1 more source

OpenEdition experiments open peer review protocols for scientific articles

open access: yes, 2015
As part of the European project OpenAIRE2020 (Open Access Infrastructure for Research in Europe toward 2020), OpenEdition is experimenting open peer review protocols, in partnership with the electronic journal VertigO and the Couperin consortium. What is
Julien Bordier
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Open Praxis, volume 10 issue 2

open access: yes, 2018
For a fifth consecutive year, Open Praxis has partnered with the Open Education Consortium for the publication of selected papers among those presented in the 2018 Open Education Global Conference, held in Delft (The Netherlands) from 24 to 26 of April ...
Inés Gil-Jaurena (ed.), various authors   +1 more
core   +1 more source

Open peer review: un esperimento

open access: yesBollettino Telematico di Filosofia Politica, 2012
Come abbiamo scritto anche su queste pagine, la revisione paritaria tradizionale è da tempo in discussione. Perché dei giudici anonimi, scelti segretamente dalla direzione di una rivista, dovrebbero garantire una valutazione accurata e imparziale dei ...
Maria Chiara Pievatolo
doaj  

Home - About - Disclaimer - Privacy