Results 61 to 70 of about 2,192,791 (336)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
A prospective study on an innovative online forum for peer reviewing of surgical science. [PDF]
Peer review is important to the scientific process. However, the present system has been criticised and accused of bias, lack of transparency, failure to detect significant breakthrough and error.
Martin Almquist +5 more
doaj +1 more source
Peer review interactions for Malaysian journals: The revamped open-peer review process [PDF]
It is said that the new trend of journal publication is moving toward open-peer review (OPR), where interaction among authors, reviewers and readers is considered crucial to the article selection and publication process.
Ahmad, Jasni, Shiratuddin, Norshuhada
core
Open peer review: an innovation in scientific publishing [PDF]
This research observes the emerging open peer review journals. In scientific publishing, transparency in peer review is a growing topic of interest for online journals. The traditional blind refereeing process has been criticized for lacking transparency.
Wang, Peiling
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Emerging trends in peer review - a survey
Classical peer review has been subject to intense criticism for slowing down the publication process, bias against specific categories of paper and author, unreliability, inability to detect errors and fraud, unethical practices, and the lack of ...
Richard eWalker, Pascal eRocha da Silva
doaj +1 more source
Open dialogue peer review: a response to Tymms, Merrell & Coe [PDF]
We welcome Peter Tymms, Christine Merrell and Robert Coe's paper as a timely contribution to an important issue. For precisely the reasons that they state, this is an area of current concern.
Ellis, Sue, McCartney, Elspeth
core
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Attitudes towards open peer review, open data and use of preprints influence scientists' engagement with those practices. Yet there is a lack of validated questionnaires that measure these attitudes.
Ksenija Baždarić +7 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

