Results 81 to 90 of about 2,234,202 (287)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Roberto Gatti, Politica, morale, moralismo

Bollettino Telematico di Filosofia Politica, 2012
Si tratta della bozza di una conferenza pisana del ciclo “Politica e sapienza” tenuta dal professor Roberto Gatti il 18 febbraio 2012.  L’autore ha scelto di offrire il suo testo alla discussione pubblica depositandolo nell’ ...
Maria Chiara Pievatolo
doaj  

What is open peer review? A systematic review [version 1; referees: 1 approved, 2 approved with reservations]

F1000Research, 2017
Background: “Open peer review” (OPR), despite being a major pillar of Open Science, has neither a standardized definition nor an agreed schema of its features and implementations.
Tony Ross-Hellauer
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

How to Peer Review for Scientific Journals?

International Journal of Advanced Medical and Health Research
Peer review is the evaluation of scientific, academic, or professional work by experts in the field. This process starts when the editor of a peer-reviewed journal sends an article or a manuscript to two or more reviewers for review.
Mukta Wyawahare
doaj   +1 more source

Peer review interactions for Malaysian journals: The revamped open-peer review process [PDF]

, 2008
It is said that the new trend of journal publication is moving toward open-peer review (OPR), where interaction among authors, reviewers and readers is considered crucial to the article selection and publication process.
Ahmad, Jasni, Shiratuddin, Norshuhada
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Open peer review

, 2016
Presented Jan. 22, 2016 at UCLA OpenCon satellite event: "Demystifying open: Open Scholarship for Graduate Students".
openaire   +1 more source

Peer Review for Journals: Evidence on Quality Control, Fairness, and Innovation [PDF]

I reviewed the published empirical evidence concerning journal peer review, which consisted of 68 papers, all but three published since 1975. Peer review improves quality, but its use to screen papers has met with limited success.
JS Armstrong
core