Results 81 to 90 of about 27,427,486 (239)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Background: “Open peer review” (OPR), despite being a major pillar of Open Science, has neither a standardized definition nor an agreed schema of its features and implementations.
Tony Ross-Hellauer
doaj +1 more source
Open peer review: pros and cons. [PDF]
Sardanelli F, Colarieti A.
europepmc +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Aaron Barlow shares his views with Sean Scanlan on the problems of traditional peer review. Barlow is Faculty Editor of Academe, the magazine of the American Association of University Professors (AAUP).
Sean Scanlan, Aaron Barlow
doaj
Acknowledgement to reviewers [PDF]
The Journal of Interdisciplinary Sciences (JIS) wishes to thank all the reviewers for their intellectual contributions in the timely reviewing of the manuscripts.
Editor-in-Chief
doaj
PeerPigeon: A Web Application to Support Generalised Peer Review
Peer Review (also known as Peer Assessment) is an important technique in learning, but can be difficult to support through e-learning due to the complexity and variety of peer review processes.
Sinclair, Patrick +2 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Open peer review, pros and cons from the perspective of an early career researcher. [PDF]
Henriquez T.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source

