Results 91 to 100 of about 27,427,486 (239)
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Making the most of peer review
Journals should publish referee reports and respond to well-founded concerns about papers after publication.
Nikolai Slavov
doaj +1 more source
Adoption of Artificial Intelligence, Preprints, Open Peer Review, Model Text Recycling Policies, Best Practice in Scholarly Publishing: Comment. [PDF]
Kleebayoon A, Wiwanitkit V.
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Research Integrity and Peer Review—past highlights and future directions
In May 2016, we launched Research Integrity and Peer Review, an international, open access journal with fully open peer review (reviewers are identified on their reports and named reports are published alongside the article) to provide a home for ...
Stephanie L. Boughton +4 more
doaj +1 more source
Reply to the Comment on Adoption of Artificial Intelligence, Preprints, Open Peer Review, Model Text Recycling Policies, Best Practice in Scholarly Publishing: Comment. [PDF]
Huh S.
europepmc +1 more source
OPEN PEER REVIEW -- Adelheid Heftberger zu einem möglichen Experiment
«And therein lies the paradox of OPR: We won’t know if it works until more of us try. So for the good of the future of science, perhaps we need to be willing to participate in an experiment of our own collective making».1 Von Adelheid Heftberger Der Peer-
Open Media Studies
core +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Open peer review commentary on building clinically relevant outcomes across the Alzheimer's disease spectrum. [PDF]
Rockwood K.
europepmc +1 more source

