Results 101 to 110 of about 668,202 (287)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Philosophy, Bullshit, and Peer Review

open access: yes, 2023
Peer review is supposed to ensure that published work, in philosophy and in other disciplines, meets high standards of rigor and interest. But many people fear that it no longer is fit to play this role. This Element examines some of their concerns.
Levy, Neil
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Edmund Burke and the issue of a conservative and liberal tradition in Italy, 1791-1945 – Call for Reviewers

open access: yesBollettino Telematico di Filosofia Politica, 2012
We are submitting the article Edmund Burke and the issue of a conservative and liberal tradition in Italy, 1791-1945 by Mauro Lenci to an experimental open peer review. Commenting is easy: you should simply register here, log in our Commentbfp site.
Maria Chiara Pievatolo
doaj  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Peer Review in OER

open access: yes, 2020
What does peer review mean in OER? Are the student reviews of an OER in the classroom more important than peer reviewing by other faculty? Come watch a recorded webinar from the Open Textbook Network and discuss peer review & OER during Open Education ...
Rebus Community, Open Textbook Network
core  

76: Open peer review

open access: yes, 2023
Peer review is typically conducted behind closed doors. There's been a recent push to make open peer review standard, but what's often left out of these conversations are the potential downsides.
Daniel Quintana, James Heathers
core  

An Interview with Aaron Barlow, editor of Academe, the magazine of the American Association of University Professors

open access: yesNANO, 2014
Aaron Barlow shares his views with Sean Scanlan on the problems of traditional peer review. Barlow is Faculty Editor of Academe, the magazine of the American Association of University Professors (AAUP).
Sean Scanlan, Aaron Barlow
doaj  

Open peer review urgently requires evidence: A call to action. [PDF]

open access: yesPLoS Biol, 2023
Ross-Hellauer T   +2 more
europepmc   +1 more source

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