Results 71 to 80 of about 668,202 (287)
The Role of the Anonymous Voice in Post-Publication Peer Review Versus Traditional Peer Review [PDF]
Traditional peer review (TPR) has several limitations and weaknesses. Post-publication peer review is one practical way to repair the ills of TPR and reinforce it.
Jaime A. Teixeira da Silva +1 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Towards a Canonical View of Peer Assessment
Peer Assessment (or Peer Review) is a popular form of reciprocal assessment where students produce feedback, or grades, for each others work. Peer Assessment activities can be extremely varied with participants taking different roles at different stages ...
Sinclair, Patrick +13 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Peer-reviewed open research data: Results of a pilot
Peer review of publications is at the core of science and primarily seen as instrument for ensuring research quality. However, it is less common to value independently the quality of the underlying data as well. In the light of the “data deluge” it makes
Grootveld, M.J. +6 more
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A prospective study on an innovative online forum for peer reviewing of surgical science. [PDF]
Peer review is important to the scientific process. However, the present system has been criticised and accused of bias, lack of transparency, failure to detect significant breakthrough and error.
Martin Almquist +5 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Open Citations and Open Peer Review: Toward a Better Thresher in Scientific Literature (Preprint) [PDF]
Open Peer Review and Open Citations need advocates. Open Access recently received significant boosts in organized support (Redalyc announcing AmerliCA; cOAlition-S announcing Plan S).
Arthur Boston
core +1 more source

