Results 161 to 170 of about 165,562 (297)

The WHO costing and budgeting tool for national action plans on antimicrobial resistance-a review and assessment of impact in Africa. [PDF]

JAC Antimicrob Resist
Mazengiya YD, Gahimbare L, Judith A, Patriarchi A, Verboom P, Fuller W, Ahmed YA.   +6 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Users’ Privacy Preference in Open Plan Offices

, 2008
The purpose of this paper is to explore managers\u27 and employees\u27 opinions regarding privacy in open plan offices and also investigate the relationship between the perception of managers and employees on visual and acoustical privacy in order to ...
Ding, Suining
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Shared leadership team: the creation, journey, lessons learned. [PDF]

Front Public Health
Joshua T, Lopez R, Wilson JS, Owino M, Love E, Schinasi L, Kaufman MJ, Waetzig E, Lovasi GS, Moore RH.   +9 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Preventing childhood drowning in New York: a state action plan. [PDF]

Inj Epidemiol
Pressley JC, McDonald MA.
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Natural illumination of deep-plan office buildings : light pipe strategies

, 2003
– Deep plans are a common practice in middle and high-rise office building design, and large\ud open plans have become the preferred office layout by modern businesses due to the flexibility of the space\ud and economic benefits achieved from maximum ...
Edmonds, Ian, Garcia Hansen, Veronica
core  

ENding HIV transmission to infants by Generating Evidence to optimise prevention and care for pregnant and postpartum Adolescent Girls and young women with HIV in Tanzania (ENGAGE): study protocol for a mixed-methods research project. [PDF]

BMJ Open
Lyatuu GW, Larsson EC, Siril H, Mbunda T, Urrio RF, Machumi L, Machang'u D, Unkels R, Mauka WI, Mahande MJ, Simba B, Festo C, Mganga A, Mfaume RS, Laizer S, Rutatinisibwa H, Kibao A, Muhode P, Njau P, Maokola W, Rwebembera A, Msangi M, Nyamhagatta MA, Sunguya BF, Naburi H, Ekström AM, Kågesten AE.   +26 more
europepmc   +1 more source