Results 121 to 130 of about 991,153 (346)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Coworking Spaces – A Source for Developing Creative Business [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2019
The effects of information technology have allowed people to choose between working at the firm's office, home office or in collaborative spaces, in open plan office environments, where they work alongside other non-affiliated professionals for a monthly
Claudia Isac
doaj  

Decentralization of land management in Madagascar : Process, innovations and observation of the first outcome [PDF]

open access: yes, 2008
Since 2005, Madagascar has committed itself into a deep land reform, based on modernization of the land administration and on decentralization of the land management to the Communes.
Andrianirina Ratsialonana, Rivo   +3 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

U.S. Government Manual 2008-2009 Edition: Department of Labor [PDF]

open access: yes, 2008
[Excerpt] The purpose of the Department of Labor is to foster, promote, and develop the welfare of the wage earners of the United States, to improve their working conditions, and to advance their opportunities for profitable employment.
U.S. Government Printing Office
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

EFEITO DA REESTRUTURAÇÃO DO AMBIENTE DE TRABALHO SOBRE A SAÚDE DE TRABALHADORES ADMINISTRATIVOS: IMPLANTAÇÃO DE OPEN-PLAN OFFICES

open access: yesAção Ergonômica, 2015
O trabalho em equipe tem sido cada vez mais incentivado, refletindo até mesmo na organização do ambiente ocupacional. Objetivando facilitar a interação tem-se observado adaptações ambientais na substituição de salas individuas por open-plan offices. Este
Gabriela Salomé Nunes   +5 more
doaj  

A systematic investigation of group differences in crossed effects of indoor environmental parameters on human comfort in open-plan offices in severe cold regions

open access: yesDevelopments in the Built Environment
This study examined group differences in the crossed effects of indoor environmental parameters on human comfort in open-plan offices in severe cold regions, considering gender, age, education, BMI and seating location.
Zheng Li   +5 more
doaj   +1 more source

An Assessment of Alternative Strategies for Increasing Access to Legal Services

open access: yes, 1980
Since the late 1930s, lawyers have argued that their services are not used to the fullest advantage by a large segment of the population. More recently, other concerned groups such as trade unions and consumer organizations also have become convinced ...
Stempel, Jeffrey W.
core  

Spring 2015, Serving Our 1,000+ International Students [PDF]

open access: yes, 2015
As the population of international students and scholars continues to grow, the integration of campus resources to serve them is becoming more and more vital.
Luksha, Kate, Nguyen, Thuy
core   +1 more source

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