Results 241 to 250 of about 991,153 (346)

Requirements and Use Cases for eHealth Solutions in Flexible Assertive Community Treatment Teams: Design Science Study. [PDF]

JMIR Form Res
Bønes E, Granja C, Solvoll T.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Comparison of sedentary time, number of steps and sit-to-stand-transitions of desk-based workers in different office environments including working from home: analysis of quantitative accelerometer data from the cross-sectional part of the SITFLEX Study. [PDF]

Scand J Work Environ Health
Sauter M, Backé E, Pfab C, Prigge M, Brendler C, Liebers F, von Löwis P, Pfeiffer A, Papenfuss F, Hegewald J.   +9 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

A systematic model for health systems to prevent and respond to health emergencies in the workplace. [PDF]

BMC Health Serv Res
Farshad AA, Yarmohammadi S, Motalebi Gh M, Hassanzadeh-Rangi N, Faghihi M, Ezati E, Khosravi Y.   +6 more
europepmc   +1 more source

Wappingers Central School District and Wappingers Central School District Office Unit, CSEA Local 1000, AFSCME, AFL-CIO, Dutchess County Educational Local 867 (2007) [PDF]

, 2007

core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Perceptions of activity-based offices are associated with employee well-being and self-reported work ability in hybrid work: a cross-sectional study. [PDF]

J Occup Health
Tulenheimo-Eklund E, Haapakangas A, Hirvonen M, Ruohomäki V, Reijula K.   +4 more
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source