Results 111 to 120 of about 1,756,114 (295)
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
RAN Virtualization: How Hard Is It to Fully Achieve?
IEEE AccessRadio Access Network (RAN) virtualization stands as a pivotal concept in the realm of 5G networks and beyond. It emerges as a viable solution not only to address energy cost concerns but also to optimize material and radio resource management.
Mihia Kassi, Soumaya Hamouda
doaj +1 more source
MOOCs: A first-hand experience on EDC MOOC and a speculation of their future impact in Higher Education [PDF]
Massive Open Online Courses (MOOCs) – a term coined by Dave Cormier back in 2008 when the first experimental MOOC ran - came to prominence in 2012 with the launch of Coursera, EdX and Udacity platforms in the United States.
Almpanis, Timos
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Big Data Mining and AnalyticsOpen Air Interface (OAI) alliance recently introduced a new disaggregated Open Radio Access Networks (O-RAN) framework for next generation telecommunications and networks. This disaggregated architecture is open, automated, software defined, virtual, and
Sunil Kumar
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Deep Learning for Intelligent and Automated Network Slicing in 5G Open RAN (ORAN) Deployment
IEEE Open Journal of the Communications Society5G and beyond networks are considered a catalyst for emerging IoT applications and services by providing ultra-reliable connectivity and massive connections to billions of IoT sensors and devices.
Shu-Ping Yeh +3 more
doaj +1 more source
Adapting LoRaWAN to the Open-RAN Architecture
IEEE NetworkThis article proposes O-LoRaWAN, an adaptation of the LoRaWAN architecture into a modular network architecture based on the Open RAN (O-RAN) principles. In our vision, standardization of the network components and interfaces will enable the reuse of network functions, and thus, foster an accelerated tailoring of the network functions to the changing ...
Sobhi Alfayoumi +2 more
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source