Results 91 to 100 of about 262,816 (254)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

High-Throughput Accelerator for Exact-MMSE Soft-Output Detection in Open RAN Systems

IEEE Access
Open Radio Access Networks (Open RANs), realized fully in software, require excessive computing resources to support time-sensitive signal-processing algorithms in the physical layer.
Thomas James Thomas, Konstantinos Nikitopoulos   +1 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Multi-task meta-initialized DQN for fast adaptation to unseen slicing tasks in O-RAN.

PLoS ONE
The open radio access network (O-RAN) architecture facilitates intelligent radio resource management via RAN intelligent controllers (RICs). Deep reinforcement learning (DRL) algorithms are integrated into RICs to address dynamic O-RAN slicing challenges.
Bosen Zeng, Xianhua Niu
doaj   +1 more source

AI/ML Enabled Automation System for Software Defined Disaggregated Open Radio Access Networks: Transforming Telecommunication Business

Big Data Mining and Analytics
Open Air Interface (OAI) alliance recently introduced a new disaggregated Open Radio Access Networks (O-RAN) framework for next generation telecommunications and networks. This disaggregated architecture is open, automated, software defined, virtual, and
Sunil Kumar
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Deep Learning for Intelligent and Automated Network Slicing in 5G Open RAN (ORAN) Deployment

IEEE Open Journal of the Communications Society
5G and beyond networks are considered a catalyst for emerging IoT applications and services by providing ultra-reliable connectivity and massive connections to billions of IoT sensors and devices.
Shu-Ping Yeh, Sonia Bhattacharya, Rashika Sharma, Hassnaa Moustafa   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

AI-RAN: The pathway to future wireless networks

Journal of Information and Intelligence
With the rapid advancement of Artificial Intelligence (AI), the Radio Access Network (RAN) is poised to undergo a transformative evolution toward the convergence of AI and RAN functionalities, referred to as the AI-RAN paradigm.
Chenyuan Feng, Howard H. Yang, Kun Guo, Wenchao Xia, Chenxi Liu, Tony Q.S. Quek   +5 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source