Results 81 to 90 of about 1,812,344 (297)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

A Measurement-Based Power Consumption Model for Networks With Intelligent Control (RIC)

IEEE Open Journal of the Communications Society
Open Radio Access Network (Open RAN) triggers a shift towards multi-vendor deployments with increased programmability, flexibility, and intelligence. Still, several critical questions remain unanswered, particularly regarding Open RAN's impact on power ...
Joao Paulo S. H. Lima, George N. Katsaros, Rahim Tafazolli, Konstantinos Nikitopoulos   +3 more
doaj   +1 more source

Toward Modular and Flexible Open RAN Implementations in 6G Networks: Traffic Steering Use Case and O-RAN xApps. [PDF]

Sensors (Basel), 2021
Dryjański M, Kułacz Ł, Kliks A.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Toward Incorporating mmWave Beam Tracking for Connected Autonomous Vehicles

IEEE Access
As we move towards the Beyond 5G/6G era, the importance of Open Radio Access Network (Open RAN) is growing significantly. While traditional RAN systems are largely controlled by specific vendors, the O-RAN alliance promotes open interfaces to enable a ...
Jin Nakazato, Kazuki Maruta, Ryo Iwaki, Sojin Ozawa, Yuki Sasaki, Tetsuya Iye, Zongdian Li, Rui Dinis   +7 more
doaj   +1 more source

The IoV Meets Open RAN: An O-RAN-based IoV Architecture

ELEKTRIKA- Journal of Electrical Engineering
The race towards a better-connected world has led to innovations in network connectivity and the embedding of intelligence into various types of devices. Intelligent devices require an intelligent network infrastructure and design in order to reach their maximum potential. Recently, the concept of Open Radio Access Networks (Open RAN, O-RAN) has gained
Kobby Obeng, Prof. Ir. Ts. Dr. Sharifah Hafizah Syed Ariffin, Nor Aishah Muhammed   +2 more
openaire   +1 more source

Open RAN Slicing with Quantum Optimization

2025 Global Information Infrastructure and Networking Symposium (GIIS)
Presented at IEEE conference ...
Keyela, Patatchona, Cherkaoui, Soumaya
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A Next-Generation Cyber-Range Framework for O-RAN and 6G Security Validation

Future Internet
The evolution towards an Open Radio Access Network (O-RAN) and 6G introduces unprecedented openness and intelligence in mobile networks, alongside significant security challenges.
Evangelos Chaskos, Nicholas Kolokotronis, Stavros Shiaeles   +2 more
doaj   +1 more source