Results 61 to 70 of about 255,903 (282)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Flexible Association and Placement for Open-RAN
IEEE INFOCOM 2024 - IEEE Conference on Computer Communications Workshops (INFOCOM WKSHPS)In modern Open RAN architectures, the classic gNB radio protocol stack is disaggregated and implemented in different virtualized components, the Centralized Unit (CU), the Distributed Unit (DU), and the Radio Unit (RU). Each of these units is deployed throughout the cloud-enabled RAN infrastructure in order to achieve users' required Quality of Service
Hojeij, Hiba +5 more
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Attacking O-RAN Interfaces: Threat Modeling, Analysis and Practical Experimentation
IEEE Open Journal of the Communications SocietyA new generation of open and disaggregated Radio Access Networks (RANs) enabling multi-vendor, flexible, and cost-effective deployments is being promoted by the Open Radio Access Network (O-RAN) Alliance.
Pau Baguer +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Intelligent O-RAN Beyond 5G: Architecture, Use Cases, Challenges, and Opportunities
IEEE AccessOpen RAN (Radio Access Network) is revolutionizing the telecom space by introducing a framework based on the concepts of virtualization and openness.
Simona Marinova, Alberto Leon-Garcia
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
AI-Native Open RAN for Non-Terrestrial Networks: An Overview
IEEE Open Journal of the Communications SocietyNon-terrestrial network (NTN) is envisioned as a critical component of Sixth Generation (6G) networks by enabling ubiquitous services and enhancing network resilience.
Jikang Deng +5 more
doaj +1 more source