Results 41 to 50 of about 346,866 (255)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Attacking O-RAN Interfaces: Threat Modeling, Analysis and Practical Experimentation

IEEE Open Journal of the Communications Society
A new generation of open and disaggregated Radio Access Networks (RANs) enabling multi-vendor, flexible, and cost-effective deployments is being promoted by the Open Radio Access Network (O-RAN) Alliance.
Pau Baguer, Girma M. Yilma, Esteban Municio, Gines Garcia-Aviles, Andres Garcia-Saavedra, Marco Liebsch, Xavier Costa-Perez   +6 more
doaj   +1 more source

Securing O-RAN Open Interfaces

IEEE Transactions on Mobile Computing
The next generation of cellular networks will be characterized by openness, intelligence, virtualization, and distributed computing. The Open Radio Access Network (Open RAN) framework represents a significant leap toward realizing these ideals, with prototype deployments taking place in both academic and industrial domains. While it holds the potential
Joshua Groen, Salvatore D'Oro, Utku Demir, Leonardo Bonati, Davide Villa, Michele Polese, Tommaso Melodia, Kaushik R. Chowdhury   +7 more
openaire   +3 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Intelligent O-RAN Beyond 5G: Architecture, Use Cases, Challenges, and Opportunities

IEEE Access
Open RAN (Radio Access Network) is revolutionizing the telecom space by introducing a framework based on the concepts of virtualization and openness.
Simona Marinova, Alberto Leon-Garcia
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Adapting LoRaWAN to the Open-RAN Architecture

IEEE Network
This article proposes O-LoRaWAN, an adaptation of the LoRaWAN architecture into a modular network architecture based on the Open RAN (O-RAN) principles. In our vision, standardization of the network components and interfaces will enable the reuse of network functions, and thus, foster an accelerated tailoring of the network functions to the changing ...
Sobhi Alfayoumi, Joan Melià-Seguí, Xavier Vilajosana   +2 more
openaire   +3 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

AI-Native Open RAN for Non-Terrestrial Networks: An Overview

IEEE Open Journal of the Communications Society
Non-terrestrial network (NTN) is envisioned as a critical component of Sixth Generation (6G) networks by enabling ubiquitous services and enhancing network resilience.
Jikang Deng, S. Fizza Hasan, Hui Zhou, Saad Al-Ahmadi, Mohamed-Slim Alouini, Daniel B. Da Costa   +5 more
doaj   +1 more source