Results 51 to 60 of about 262,816 (254)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Securing O-RAN Open Interfaces

IEEE Transactions on Mobile Computing
The next generation of cellular networks will be characterized by openness, intelligence, virtualization, and distributed computing. The Open Radio Access Network (Open RAN) framework represents a significant leap toward realizing these ideals, with prototype deployments taking place in both academic and industrial domains. While it holds the potential
Joshua Groen, Salvatore D'Oro, Utku Demir, Leonardo Bonati, Davide Villa, Michele Polese, Tommaso Melodia, Kaushik R. Chowdhury   +7 more
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Adapting LoRaWAN to the Open-RAN Architecture

IEEE Network
This article proposes O-LoRaWAN, an adaptation of the LoRaWAN architecture into a modular network architecture based on the Open RAN (O-RAN) principles. In our vision, standardization of the network components and interfaces will enable the reuse of network functions, and thus, foster an accelerated tailoring of the network functions to the changing ...
Sobhi Alfayoumi, Joan Melià-Seguí, Xavier Vilajosana   +2 more
openaire   +2 more sources

Multi-UE 5G RAN Measurements: A Gamut of Architectural Options

IEEE Access
The Radio Access Network (RAN) of Fifth Generation (5G) communication systems critically influences the overall performance and cost of a 5G system.
Andreas Ingo Grohmann, Mauri Seidel, Sebastian A. W. Itting, Ray-Guang Cheng, Martin Reisslein, Frank H. P. Fitzek   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Open RAN testbeds with controlled air mobility

Computer Communications
With its promise of increasing softwarization, improving disaggregability, and creating an open-source based ecosystem in the area of Radio Access Networks, the idea of Open RAN has generated rising interest in the community. Even as the community races to provide and verify complete Open RAN systems, the importance of verification of systems based on ...
Magreth Mushi, Yuchen Liu 0001, Shreyas Sreenivasa, Özgür Özdemir, Ismail Güvenç, Mihail L. Sichitiu, Rudra Dutta, Russ Gyurek   +7 more
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source