C12orf5 (chromosome 12 open reading frame 5) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2018 Review on C12orf5, with data on DNA/RNA, on the protein encoded and where the gene is ...
Bartrons Bach, Ramon +5 more
core +6 more sources
Simple Procedure for Creation of In-Frame Deletion Mutations Throughout an Open Reading Frame
BioTechniques, 1996 A general method is presented for randomly mutagenizing open reading frames (ORF) to generate in-frame deletions and insertions. Theprotocol requires expression of the ORF of interest as a hybrid ORF-β-galactosidase fusion protein.
John H. Ludes-Meyers, Van G. Wilson
doaj +4 more sources
Translational control of murine adiponectin expression by an upstream open reading frame element [PDF]
RNA Biology, 2023 Adiponectin, an adipocyte-specific secretory protein encoded by the ADIPOQ gene has a causal role in insulin resistance. Anti-diabetic drugs increase plasma adiponectin by a poorly understood, post-transcriptional mechanism enhancing insulin sensitivity.
Kommireddy Vasu +6 more
doaj +2 more sources
Open-reading frame (ORF) [PDF]
Springer Reference Medizin, 2019 J. Arnemann
semanticscholar +4 more sources
An upstream open reading frame modulates ebola virus polymerase translation and virus replication. [PDF]
PLoS Pathogens, 2013 Ebolaviruses, highly lethal zoonotic pathogens, possess longer genomes than most other non-segmented negative-strand RNA viruses due in part to long 5' and 3' untranslated regions (UTRs) present in the seven viral transcriptional units. To date, specific
Reed S Shabman +7 more
doaj +6 more sources
Nucleotide sequence of the human c‐myc locus: provocative open reading frame within the first exon. [PDF]
EMBO Journal, 1984 Claude Gazin +6 more
semanticscholar +2 more sources
HAltORF: a database of predicted out-of-frame alternative open reading frames in human [PDF]
Database, 2012 Human alternative open reading frames (HAltORF) is a publicly available and searchable online database referencing putative products of out-of-frame alternative translation initiation (ATI) in human mRNAs.
Benoît Vanderperre +2 more
semanticscholar +3 more sources
A perspective on mammalian upstream open reading frame function
The International Journal of Biochemistry & Cell Biology, 2013 Post-transcriptional control makes a major contribution to the overall regulation of gene expression pathway. Within the cytoplasm this is mediated by a combination of regulatory RNA motifs within the 5' and 3' untranslated regions of mRNAs and their interacting protein/RNA partners.
J. Somers, T. Pöyry, A. Willis
semanticscholar +4 more sources
Mitochondrial-Encoded Peptide MOTS-c, Diabetes, and Aging-Related Diseases [PDF]
Diabetes & Metabolism Journal, 2023 Mitochondria are complex metabolic organelles with manifold pathophysiological implications in diabetes. Currently published mitochondrial-encoded peptides, which are expressed from the mitochondrial open reading frame of the 12S ribosomal RNA type-c ...
Byung Soo Kong +2 more
doaj +1 more source
Open reading frame cloning: identification, cloning, and expression of open reading frame DNA. [PDF]
Proceedings of the National Academy of Sciences, 1982 A plasmid was constructed that facilitates the cloning and expression of open reading frame DNA. A DNA fragment containing a bacterial promoter and the amino terminus of the cI gene of bacteriophage lambda was fused to an amino-terminally deleted version of the lacZ gene.
Hildur V. Colot +3 more
openaire +3 more sources