Results 21 to 30 of about 276,768 (304)
Novel exon of mammalian ADAR2 extends open reading frame.
PLoS ONE, 2009 BackgroundThe post-transcriptional processing of pre-mRNAs by RNA editing contributes significantly to the complexity of the mammalian transcriptome. RNA editing by site-selective A-to-I modification also regulates protein function through recoding of ...
Stefan Maas, Willemijn M Gommans
doaj +1 more source
Open reading frame cloning: identification, cloning, and expression of open reading frame DNA. [PDF]
Proceedings of the National Academy of Sciences, 1982 A plasmid was constructed that facilitates the cloning and expression of open reading frame DNA. A DNA fragment containing a bacterial promoter and the amino terminus of the cI gene of bacteriophage lambda was fused to an amino-terminally deleted version of the lacZ gene.
M R, Gray +3 more
openaire +2 more sources
Nature Communications, 2019 The majority of enterovirus proteins are encoded as polyprotein in one open reading frame. Here, Guo et al. characterize a second open reading frame in human enteroviruses and show that it is important for viral particle release, particularly in ...
Haoran Guo +9 more
doaj +1 more source
The Hepatitis E Virus Open Reading Frame 2 Protein: Beyond Viral Capsid
Frontiers in Microbiology, 2021 Hepatitis E virus (HEV) is a zoonotic pathogen causing hepatitis in both human and animal hosts, which is responsible for acute hepatitis E outbreaks worldwide. The 7.2 kb genome of the HEV encodes three well-defined open reading frames (ORFs), where the
Zhaobin Zhou +6 more
doaj +1 more source
Journal of Biomedical Science, 2022 A short open reading frame (sORFs) constitutes ≤ 300 bases, encoding a microprotein or sORF-encoded protein (SEP) which comprises ≤ 100 amino acids. Traditionally dismissed by genome annotation pipelines as meaningless noise, sORFs were found to possess ...
Alyssa Zi-Xin Leong +5 more
doaj +1 more source
Noise reduction by upstream open reading frames
Nature Plants, 2022 AbstractGene expression is prone to burst production, making it a highly noisy process that requires additional controls. Upstream open reading frames (uORFs) are widely present in the 5′ leader sequences of 30–50% of eukaryotic messenger RNAs1–3. The translation of uORFs can repress the translation efficiency of the downstream main coding sequences ...
Ho-Wei Wu +5 more
openaire +2 more sources
uPEPperoni: an online tool for upstream open reading frame location and analysis of transcript conservation [PDF]
, 2014 Background: Several small open reading frames located within the 5' untranslated regions of mRNAs have recently been shown to be translated. In humans, about 50% of mRNAs contain at least one upstream open reading frame representing a large resource of ...
Beatson, Scott A. +15 more
core +1 more source
Primers used to amplify four overlapping fragments of the vhs open reading frame, UL41.
, 2023 Primers used to amplify four overlapping fragments of the vhs open reading frame, UL41.
Emma L. Wise (4911469) +4 more
core +1 more source
AlterORF: a database of alternate open reading frames [PDF]
Nucleic Acids Research, 2007 AlterORF is a searchable database that contains information regarding alternate open reading frames (ORFs) for over 1.5 million genes in 481 prokaryotic genomes. The objective of the database is to provide a platform for improving genome annotation and to serve as an aid for the identification of prokaryotic genes that potentially encode proteins in ...
Inti Pedroso +6 more
openaire +9 more sources
Expression of protein encoded by varicella-zoster virus open reading frame 63 in latently infected human ganglionic neurons [PDF]
, 1996 peer reviewedThe ganglionic cell type in which varicellazoster virus (VZV) is latent in humans was analyzed by using antibodies raised against in vitro-expressed VZV open reading frame 63 protein, VZV open reading frame 63 protein was detected ...
Gilden, Donald H. +6 more
core +1 more source