Results 111 to 120 of about 31,544,274 (308)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Open Access, Open Monographs, Open Data, Open Peer Review
eLucidate, 2019 Last year’s UKeiG professional development programme was a huge success attracting delegates from all sectors and disciplines of the library and information profession. UKeiG Chair David Ball’s workshop – “Open Access, Open Monographs, Open Data, Open Peer Review” – provided food for thought and a state-of-the-art overview of the complex issues around ...
openaire +1 more source
Other title: Employment Security Board of Review
, 1983 Includes bibliographical ...
Connecticut. General Assembly. Legislative Program Review and Investigations Committee.
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The usability of open source software: analysis and prospects [PDF]
, 2006 Open source communities have successfully developed many pieces of software although most computer users only use proprietary applications. The usability of open source software is often regarded as one reason for this limited distribution. In this paper
Nichols, David M., Twidale, Michael B.
core
Texas Education Review, Winter 2025 [PDF]
Table of Contents: Open Call Articles -- Utilizing Complexity Theory to Examine the Texas Science of Teaching Reading Standards / by Lammert & Godrey (p.
Texas Education Review
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
OPEN PEER REVIEW -- Adelheid Heftberger zu einem möglichen Experiment
, 2018 «And therein lies the paradox of OPR: We won’t know if it works until more of us try. So for the good of the future of science, perhaps we need to be willing to participate in an experiment of our own collective making».1 Von Adelheid Heftberger Der Peer-
Open Media Studies
core +1 more source