Results 51 to 60 of about 10,762,244 (291)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Learning to share and sharing to learn – professionaldevelopment of language teachers in HE to foster open educational practices [PDF]

, 2013
This case study presents the staff-development perspective of the ‘Collaborative Writing and Peer Review Project’ developed at the Department of Languages, at the Open University, UK, between November 2011 and March 2012.
Duensing, Annette, Gallardo, Matilde, Heiser, Sarah   +2 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Usability and open source software. [PDF]

, 2002
Open source communities have successfully developed many pieces of software although most computer users only use proprietary applications. The usability of open source software is often regarded as one reason for this limited distribution. In this paper
Nichols, David M., Twidale, Michael B.
core   +1 more source

Open access + open review

, 2004
Richard Gallagher, Above and Beyond Open Access, <em> TheScientist </em> , March 29, 2004.
openaire   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Frozen and Invariant Quantum Discord under Local Dephasing Noise

, 2017
In this chapter, we intend to explore and review some remarkable dynamical properties of quantum discord under various different open quantum system models.
A Auyuanet, A Brodutch, A Rosario, A Streltsov, A Streltsov, A Wehrl, AW Chin, B Aaronson, B Bellomo, B Bellomo, B Dakic, B Groisman, B Schumacher, B Wang, B You, BP Lanyon, C Addis, C Addis, C Arenz, C Uchiyama, CW Gardiner, D Cavalcanti, EG Carnio, EL Hahn, F Galve, FF Fanchini, FM Paula, G Karpat, G Lindblad, GM Palma, GR Fleming, GS Uhrig, GS Uhrig, H Ollivier, H-P Breuer, J Luczka, J Maziero, J-S Xu, J-S Xu, J-S Zhang, JD Montealegre, JH Reina, JPG Pinto, K Khodjasteh, K Khodjasteh, K Modi, K Modi, K Modi, L Henderson, L Mazzola, L Mazzola, L Viola, M Ali, M Cianciaruso, MA Cirone, MA Nielsen, MA Schlosshauer, MF Cornélio, MJ Biercuk, NJ Cerf, P Haikka, P Haikka, R Auccaise, R Lo Franco, S Boixo, S Daffer, S Luo, S Singha Roy, T Werlang, T Yu, T Yu, TE Hodgson, TE Hodgson, TK Chuan, U Weiss, V Madhok, ZY Sun   +76 more
core   +1 more source

Open Science roles for libraries

Knjižnica
Purpose: To give a review of the significance of Open Science for libraries in the context of the wider Open movement, with international perspectives and examples from national, academic, and public libraries.
David Bawden, Lyn Robinson
doaj   +1 more source

Open review, open commentary, open debate

, 2006
Andrew I. Dayton, Beyond Open Access: Open Discourse, the next great equalizer, Retrovirology, August 30, 2006.
openaire   +1 more source