Results 121 to 130 of about 1,565,431 (306)
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Code Forking, Governance, and Sustainability in Open Source Software [PDF]
Technology Innovation Management Review, 2013 The right to fork open source code is at the core of open source licensing. All open source licenses grant the right to fork their code, that is to start a new development effort using an existing code as its base.
Juho Lindman, Linus Nyman
doaj
Research Tool Patents and Free-Libre Biotechnology: A Unified Perspective. [PDF]
This paper proposes a unified conceptual framework to analyse the multiple role and consequences of patents in the case of biotechnology research tools. We argue that the knowledge/information and independent/complementary nature of research tools define
Jean Pierre Wack, Julien Pénin
core
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
A Developers Bill of Rights: What Open Source Developers Want in a Software License [PDF]
In this paper, we study open source developers' perspectives on the nature and structure of software licenses as well as the processes through which these licenses are designed.
MacCormack, Alan
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
OPEN INNOVATION AND THE COMPARISON BETWEEN STARTUPS AND INCUMBENT FIRMS IN SPAIN
Revista Galega de Economía, 2017 This study compares the open innovation strategy between startups and incumbent firms over a period of ten years (2004-2013). Using a sample of startups and incumbent Spanish firms, we find that they differ considerably, and that this has implications ...
doaj +1 more source
Network of Tinkerers: A Model of Open-Source Technology Innovation [PDF]
Airplanes were invented by hobbyists and experimenters, and some personal computers were as well. Similarly, many open-source software developers are interested in the software they make, and not focused on profit.
Meyer, Peter B.
core
YIMBY Generation – yes in my back yard! UK householders pioneering microgeneration heat [PDF]
, 2008 This report summarises the responses to a survey of over 900 households (the largest such UK study to date) who were considering or buying microgeneration heat technologies.
Abelman, Jennie +2 more
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