Results 121 to 130 of about 239,741 (340)

Lost Sisters Found: TESS and Gaia Reveal a Dissolving Pleiades Complex

open access: yesThe Astrophysical Journal
Most star clusters dissolve into the Galaxy over tens to hundreds of millions of years after they form. While recent Gaia studies have honed our view of cluster dispersal, the exact chronology of which star formation events begat which star cluster ...
Andrew W. Boyle   +2 more
doaj   +1 more source

Symbiotic stars in Galactic open clusters

open access: yes
17 pages, 3 figures, accepted for publication in ...
Kueß, Lukas, Paunzen, Ernst
openaire   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Velocity Dispersion of the Open Cluster NGC 2571 by Radial Velocities and Proper Motions

open access: yesThe Astronomical Journal
We use a kernel density estimator method to evaluate the stellar velocity dispersion in the open cluster NGC 2571. We derive the 3D velocity dispersion using both proper motions as extracted from Gaia Data Release 3 and single-epoch radial velocities as ...
Maxim V. Kulesh   +5 more
doaj   +1 more source

Flare Stars as Age Indicators in Open Clusters [PDF]

open access: yesSymposium - International Astronomical Union, 1990
A new set of isochrones derived from overshooting evolutionary models, allows one to give a homogeneous age determination for open clusters with solar chemical composition and in a range of age 4 107 ÷ 1.5 109 yr. In this context is derived an empirical new age calibration - absolute magnitude of the supposed brightest flare star in a cluster versus ...
openaire   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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