Results 121 to 130 of about 344,290 (331)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Li Evolution among Stars of Low/Intermediate Mass: the Metal-deficient Open Cluster NGC 2204

open access: yesThe Astronomical Journal
We have analyzed high-dispersion spectra in the Li 6708 Å region for 167 stars within the anticenter cluster NGC 2204. From 105 probable members, abundance analysis of 45 evolved stars produces [Fe/H] = −0.40 ± 0.12, [Si/Fe] = 0.14 ± 0.12, [Ca/Fe] = 0.29
Barbara J. Anthony-Twarog   +4 more
doaj   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

open access: yesMolecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin   +10 more
wiley   +1 more source

Probing the Nature of Rotation in the Pleiades, Alpha Persei, and Hyades Clusters

open access: yesThe Astrophysical Journal
Unraveling the internal kinematics of open clusters is crucial for understanding their formation and evolution. However, there is a dearth of research on this topic, primarily due to the lack of high-quality kinematic data.
C. J. Hao   +7 more
doaj   +1 more source

Ultracool dwarfs in open clusters and star-forming regions

open access: yesEPJ Web of Conferences, 2013
In this contribution I review the results of the UKIRT Infrared Deep Sky Survey (UKIDSS) Galactic Clusters Survey (GCS) on the Initial Mass Function (IMF) and the current searches for young T dwarfs in open clusters and star-forming regions.
Lodieu Nicolas
doaj   +1 more source

A multicolour CCD photometric and mass function study of the distant southern open star clusters NGC 3105, NGC 3603, Melotte 105, Hogg 15, NGC 4815, Pismis 20 and NGC 6253

open access: yes, 2001
We derive cluster parameters and mass functions from new UBVRI CCD photometric observations of ~3500 stars reaching down to V ~20mag for the distant southern open star clusters NGC 3105, NGC 3603, Melotte 105, Hogg 15, NGC 4815, Pismis 20 and NGC 6253 ...
R. Sagar, U. Munari, K. S. Boer
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Double Compact Binary Merger Rate Density in Open Star Clusters: Black Holes, Neutron Stars, and White Dwarfs

open access: yesThe Astrophysical Journal
Studying compact object binary mergers in star clusters is crucial for understanding stellar evolution and dynamical interactions in galaxies. Open clusters in particular are more abundant over cosmic time than globular clusters.
Savannah Cary   +3 more
doaj   +1 more source

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