Results 131 to 140 of about 344,290 (331)

Optical Linear Polarization toward the Open Star Cluster Casado Alessi 1 [PDF]

, 2020
Sadhana Singh, Jeewan C. Pandey, R. K. S. Yadav, Biman J. Medhi, Sadhana Singh, Jeewan C. Pandey, R. K. S. Yadav, Biman J. Medhi   +7 more
openalex   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Quantifying the Limits of TESS Stellar Rotation Measurements with the K2-TESS Overlap

The Astrophysical Journal
The Transiting Exoplanet Survey Satellite (TESS) has provided stellar rotation periods across much of the sky through high-precision light curves, but the reliability and completeness of these measurements require careful evaluation.
Andrew W. Boyle, Andrew W. Mann, Jonathan Bush   +2 more
doaj   +1 more source

New stellar members of the Coma Berenices open star cluster [PDF]

, 2005
S. L. Casewell, R. F. Jameson, P. D. Dobbie   +2 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Open star clusters in the Milky Way [PDF]

, 2017
Dana Kovaleva, А. Э. Пискунов, Nina V. Kharchenko, S. Röser, E. Schilbach, R.‐D. Scholz, S. Reffert, Steffi X. Yen   +7 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Compact Binary Formation in Open Star Clusters II: Difficulty of Gaia NS formation in low-mass star clusters

The Open Journal of Astrophysics
Gaia mission offers opportunities to search for compact binaries not involved in binary interactions (hereafter inert compact binaries), and results in the discoveries of binaries containing one black hole (BH) or one neutron star (NS), called "Gaia BHs''
Ataru Tanikawa, Long Wang, Michiko S. Fujii   +2 more
doaj   +1 more source

Massive Clusters and OB Associations as Output of Massive Star Formation in Gaia Era

Universe
Over the past two decades, our understanding of star formation has undergone a major shift, driven by a wealth of data from infrared, submillimeter and radio surveys. The emerging view depicts star formation as a hierarchical process, which predominantly
Ignacio Negueruela
doaj   +1 more source