Results 31 to 40 of about 145,685 (217)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Estimating Single Layer Bi-Channel Neural Networks Architecture for Speed Control of Variable Reluctance Motors

open access: yesEnergies
This study explores the speed adjustment characteristics of the adaptive control of estimated single-layer Bi-channel neural networks (NNs) for Variable Reluctance Motor (VRM) drives.
Hamad Alharkan
doaj   +1 more source

LOW- CAPACITY SLAUGHTERHOUSES STRUCTURAL ADJUSTMENT FOR THE APPROVAL PROVIDED FOR BY 853/2004 REGULATION. EXPERIENCES OF THE LOCAL SANITARY AUTHORITY OF THE PROVINCE OF BERGAMO

open access: yesItalian Journal of Food Safety, 2011
For effect of CE 853/04 Regulation slaughterhouses authorized as low-capacity establishments under 91/497/CEE directive and 286/94 Decree, had to obtain the approval by 31/12/2009 to continue operating.
E. Paladino   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Intelligent adjustment for power system operation mode based on deep reinforcement learning

open access: yesiEnergy
Power flow adjustment is a sequential decision problem. The operator makes decisions to ensure that the power flow meets the system's operational constraints, thereby obtaining a typical operating mode power flow.
Wei Hu   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Balancing tension in transferred slips in some dynamic procedures for claw finger correction

open access: yesIndian Journal of Plastic Surgery, 2005
The adjustment of tension on the tendon slips which are being inserted to correct finger clawing, is the critical step in claw finger correction procedures.
G M Malaviya
doaj   +3 more sources

Capacitance Control on the Wire Production Line

open access: yesMATEC Web of Conferences, 2016
The paper presents technical implementation of the electricalcapacitive method to perform in-process measurement of the capacitance per unit length of a single-core electric wire. The design of the electrocapacitive measuring transducer is proposed.
Goldshtein Alexander   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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