Results 41 to 50 of about 145,685 (217)

ESTIMATION OF THE RELATION BETWEEN WEIBULL SEA CLUTTER AND THE CA-CFAR SCALE FACTOR

Ingeniería, 2015
When radars operate in coastal or offshore environments, an undesired signal known as clutter appears as background in the measurements. The CA-CFAR detector is the classic solution for the detection of targets inside clutter, typically using a fixed ...
José Raúl Machado Fernández
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Smartphone-assisted Camera-Based Mastoidectomy Training Unit (CBMT): a pilot randomized crossover study of cadaveric temporal bone dissection

The Egyptian Journal of Otolaryngology
Introduction Temporal bone dissection is a foundational component of otolaryngology surgical training, traditionally performed under operating microscopes that are costly and unavailable in many resource-constrained institutions. We describe and evaluate
Sanchit Bajpai, Gaurav Kumar, Neehal Zuturu, Saurabh Kumar Jaiswal, Rica Singh, Rahul Dashrath Kanojia   +5 more
doaj   +1 more source

Aerodynamic uplift force improvement in single-strip high-speed pantograph via key parameter regulation with mechanism investigation

Theoretical and Applied Mechanics Letters
This study addresses the significant disparity in aerodynamic uplift forces experienced by single-strip high-speed pantographs under different operating directions.
Yafeng Zou, Xianghong Xu, Rui Zhou, Zichen Liu, Liming Lin   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Problems of organization of operating conditions of large heat supply systems and their solutions based on multilevel modeling†

E3S Web of Conferences, 2018
The paper unveils relevance of applying the methodology of multi-level modeling of thermal-hydraulic conditions of heat supply systems (HSS) and the software which are realized in the informationcomputing system “ANGARA-TS”, which make possible ...
Shalaginiva Zoya I., Tokarev Vyacheslav V.   +1 more
doaj   +1 more source

Asymmetric targeting of corporate cash holdings and financial constraints in Pakistani firms [PDF]

Journal of Asian Business and Economic Studies, 2019
Purpose – The purpose of this paper is to investigate the asymmetric adjustment of cash holdings in Pakistani firms for above and below target firms. Design/methodology/approach – The study employs generalized method of moments (GMM) to investigate the ...
Ghulam Ayehsa Siddiqua, Ajid ur Rehman, Shahzad Hussain   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source