Results 71 to 80 of about 737,496 (327)

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Perceptually based parameter adjustments for video processing operations [PDF]

open access: yesACM SIGGRAPH 2014 Talks, 2014
Extensive post processing plays a central role in modern video production pipelines. A problem in this context is that many filters and processing operators are very sensitive to parameter settings ...
Eilertsen, Gabriel   +3 more
openaire   +3 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

TO THE QUESTION OF FUZZY EXPERT SYSTEM CONSTRUCTING PRODUCTION TYPE FOR TECHNOLOGICAL ADJUSTMENT OF MACHINES

open access: yesВестник Донского государственного технического университета, 2018
The structure and interrelations of subsystems of expert system for of a combine's harvester technological adjustment is considered. expert system's operating modes and various aspects of representation of knowledge are described.
A.K. TUGENGOLD   +2 more
doaj  

Adjustable Fusion to Support Cyber Security Operators [PDF]

open access: yes, 2015
Cyber security operators use Security Information and Event Management systems to process and summarize the huge amount of heterogeneous logs and alerts. However, these systems do not give to the operator a concise view of the attack status or context, a mandatory feature to understand and remediate properly a threat.
Claire Laudy   +5 more
openaire   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

TO THE QUESTION OF FUZZY EXPERT SYSTEM CONSTRUCTING PRODUCTION TYPE FOR TECHNOLOGICAL ADJUSTMENT OF MACHINES

open access: yesAdvanced Engineering Research, 2008
The structure and interrelations of subsystems of expert system for of a combine's harvester technological adjustment is considered. expert system's operating modes and various aspects of representation of knowledge are described.
A.K. TUGENGOLD   +2 more
doaj  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

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