Results 71 to 80 of about 5,322,488 (334)

TO THE QUESTION OF FUZZY EXPERT SYSTEM CONSTRUCTING PRODUCTION TYPE FOR TECHNOLOGICAL ADJUSTMENT OF MACHINES

open access: yesВестник Донского государственного технического университета, 2018
The structure and interrelations of subsystems of expert system for of a combine's harvester technological adjustment is considered. expert system's operating modes and various aspects of representation of knowledge are described.
A.K. TUGENGOLD   +2 more
doaj  

Adjustable Fusion to Support Cyber Security Operators [PDF]

open access: yes, 2015
Cyber security operators use Security Information and Event Management systems to process and summarize the huge amount of heterogeneous logs and alerts. However, these systems do not give to the operator a concise view of the attack status or context, a mandatory feature to understand and remediate properly a threat.
Claire Laudy   +5 more
openaire   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

TO THE QUESTION OF FUZZY EXPERT SYSTEM CONSTRUCTING PRODUCTION TYPE FOR TECHNOLOGICAL ADJUSTMENT OF MACHINES

open access: yesAdvanced Engineering Research, 2008
The structure and interrelations of subsystems of expert system for of a combine's harvester technological adjustment is considered. expert system's operating modes and various aspects of representation of knowledge are described.
A.K. TUGENGOLD   +2 more
doaj  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Study of Supervisory Control Implementation in A Small Scale Variable Speed Wind Turbine

open access: yesE3S Web of Conferences, 2018
In relation to improve wind energy production, efforts to increase the extraction of wind energy should be done when there is a decrease in wind power. The decline occurs when there is a change in wind speed. At low wind speed operating range, such as in
Indriawati Katherin   +3 more
doaj   +1 more source

Optimizing Tigertriever adjustable stentriever technique: Operators’ experience

open access: yesInterventional Neuroradiology
The Tigertriever is a novel, radially adjustable stentriever that addresses limitations in traditional mechanical thrombectomy devices by providing enhanced user control over clot integration. This provides the ability to adapt to patient-specific factors such as varying vessel sizes and clot compositions and may be particularly crucial for ensuring ...
Brian Jankowitz   +25 more
openaire   +3 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

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