Results 71 to 80 of about 2,116,565 (263)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The Brazilian Fiscal Adjustment

open access: yes, 2006
This chapter discusses fiscal adjustment in Brazil since macroeconomic stabilisation in the mid-1990s. It is argued that the authorities' growing awareness of the need for fiscal discipline was as important as the pace of structural reforms for ...
Marcio Ronci   +3 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Basic Questions and Answers on Agricultural Adjustment [PDF]

open access: yes
[Answers to:] Why is National Agricultural Adjustment Necessary? What Is the Nation's Agricultural Policy? What Do Farmers Ask? What Was the Farmer’s Share? How Could One Surplus Cause Another? Why Did Farm Debts Increase?
Agricultural Adjustment Administration
core   +1 more source

Operating leases and the assessment of lease-debt substitutability [PDF]

open access: yes, 2000
Operating leases are estimated in the current paper to be approximately thirteen times larger than finance leases, on average. In recognition of this, the paper investigates the degree of substitutability between leasing and non-lease debt using a ...
Goodacre, Alan   +6 more
core   +1 more source

Research on the adjustment mechanism of inlet guide vanes in axial compressors

open access: yesXibei Gongye Daxue Xuebao
To further elucidate the adjustment mechanism of inlet guide vanes in axial compressors of aero-engines, this paper investigates a 1.5-stage high-load compressor using numerical simulation methods. This study comprehensively examines the influence law of
YAO Yao   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Chairman's report for the period ending ... /

open access: yes, 1919
Mode of access: Internet.Continued by: National Adjustment Commission. Report of the executive secretary of the National Adjustment Commission for the period ..
National Adjustment Commission.
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Medical District

open access: yes, 1950
An aerial image of the Medical Center.

core  

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