Results 71 to 80 of about 807,503 (348)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Financial statement analysis of the steel industry (period 2013-2017) [PDF]
, 2019 The main objective of this project is the economic financial analysis of three companies: Acerin ox Europa S.A.U., Siderúrgica Sevillana, S.A., and ArcelorMittal Sestao, S.L.
Morales Arancibia, Laura Romina
core
Selective maintenance optimisation for series-parallel systems alternating missions and scheduled breaks with stochastic durations [PDF]
, 2016 This paper deals with the selective maintenance problem for a multi-component system performing consecutive missions separated by scheduled breaks.
Aghezzaf, El-Houssaine +3 more
core +4 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
How the strategic review of charges 2002-06 casts a long shadow over future water charges in Scotland [PDF]
, 2006 The findings of the research described in this paper are that there were significant errors made in the setting of water charges in 2002-06 in Scotland, such that there was substantial overcharging of customers. This will continue at a lesser extent over
Cuthbert, Jim, Cuthbert, Margaret
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Advanced Engineering Research, 2008 The structure and interrelations of subsystems of expert system for of a combine's harvester technological adjustment is considered. expert system's operating modes and various aspects of representation of knowledge are described.
A.K. TUGENGOLD +2 more
doaj
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Вестник Донского государственного технического университета, 2018 The structure and interrelations of subsystems of expert system for of a combine's harvester technological adjustment is considered. expert system's operating modes and various aspects of representation of knowledge are described.
A.K. TUGENGOLD +2 more
doaj