Results 81 to 90 of about 719,305 (325)

The impact of regulatory reforms on cost structure, ownership and competition in Indian banking [PDF]

open access: yes, 2010
This paper evaluates the impact of financial sector reforms on the cost structure characteristics and on the ownership–cost efficiency relationship in Indian banking.
Alessandra Ferrari   +35 more
core   +2 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

TO THE QUESTION OF FUZZY EXPERT SYSTEM CONSTRUCTING PRODUCTION TYPE FOR TECHNOLOGICAL ADJUSTMENT OF MACHINES

open access: yesВестник Донского государственного технического университета, 2018
The structure and interrelations of subsystems of expert system for of a combine's harvester technological adjustment is considered. expert system's operating modes and various aspects of representation of knowledge are described.
A.K. TUGENGOLD   +2 more
doaj  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

TO THE QUESTION OF FUZZY EXPERT SYSTEM CONSTRUCTING PRODUCTION TYPE FOR TECHNOLOGICAL ADJUSTMENT OF MACHINES

open access: yesAdvanced Engineering Research, 2008
The structure and interrelations of subsystems of expert system for of a combine's harvester technological adjustment is considered. expert system's operating modes and various aspects of representation of knowledge are described.
A.K. TUGENGOLD   +2 more
doaj  

Adjustable Fusion to Support Cyber Security Operators [PDF]

open access: yes, 2015
Cyber security operators use Security Information and Event Management systems to process and summarize the huge amount of heterogeneous logs and alerts. However, these systems do not give to the operator a concise view of the attack status or context, a mandatory feature to understand and remediate properly a threat.
Claire Laudy   +5 more
openaire   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

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