Results 81 to 90 of about 5,322,488 (334)

Predicting Operating Income via a Generalized Operating-Leverage Model

open access: yesInternational Journal of Financial Studies
We propose a generalized, practitioner-oriented operating-leverage model for predicting operating income using net sales, cost of sales, depreciation, and SG&A.
Sherwood Lane Lambert   +2 more
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Coarse and Fine Two-stage Fast Adjustment of the Ring Platform for Reactor Coolant Pump Bolt Detection based on Decoupling Parallel Mechanism

open access: yesJixie chuandong, 2021
The ring platform serves as the movement and operating benchmark for the online inspection of the nuclear reactor coolant pump bolts,its rapid and high-precision adjustment is the key to whether the bolt online inspection can proceed successfully. Aiming
Shisen Lin   +7 more
doaj  

An Expert System for Train Operation Adjustment of Shinkansen

open access: yesIFAC Proceedings Volumes, 1997
Abstract This paper presents an expert system for train operation adjustment of the Tokaido and Sanyo Shinkansen lines, called UWS for short. We have applied the problem solving architecture of ESTRAC-III to this system. The ESTRAC is the first application of expert systems approach to railway scheduling problems and the architecture is designed to ...
T. Seto   +5 more
openaire   +2 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Numerical parametric study of a Kaplan turbine incorporated with a sub runner considering analysis of hydraulic dissipation

open access: yesResults in Engineering
In this paper, a novel approach on Kaplan turbines, proposed and published in a US patent, has been investigated numerically using CFD tool. This approach includes the incorporation of an extra runner, called sub runner, into the main runner of a typical
Amirhossein Khoddami   +4 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

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