Results 31 to 40 of about 494,359 (316)

The effects of the forgetting curve in the training of knee arthroplasty surgical instrument nurses: a pilot randomized controlled trial

BMC Nursing
Objective This study aimed to compare the conventional review teaching method with the forgetting curve-based teaching method in the training of novice knee replacement surgical instrument nurses.
Lin Zhang, Siwei Chen, Qimei Liang, Shuchen Wang, Zhanhua Han, Jingjuan Huang, Zeyong Zhang   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Structural and psychological empowerment in relation to nurse job satisfaction and burnout: a systematic review and meta-analysis

BMC Health Services Research
Objective To concurrently evaluate the impact of both structural empowerment (SE) and psychological empowerment (PE) on the dual outcomes of nurse job satisfaction and burnout, and to compare findings with published meta-analyses to clarify incremental ...
Yang Li, Xuyan Liu, Ying Liu, Yuying Zhao, Zhaomei Meng   +4 more
doaj   +1 more source

LINC01614 Promotes Colorectal Cancer Cell Growth and Migration by Regulating miR-217-5p/HMGA1 Axis

Analytical Cellular Pathology, 2023
Colorectal cancer (CRC) substantially contributes to cancer-related deaths worldwide. Recently, a long non-coding RNA (lncRNA), LINC01614, has emerged as a vital gene regulator in cancer progression.
Jiwei Jia, Pei Guo, Li Zhang, Wenqing Kong, Fangfang Wang   +4 more
doaj   +1 more source

Operating room (OR) requirements

European Journal of Trauma and Emergency Surgery
Abstract The International Health Facility Guidelines 2023 provide critical recommendations for operating room (OR) design and management, addressing layout, equipment specifications, and safety protocols.
Pfeifer, Roman, Hildebrand, Frank, Halvachizadeh, Sascha   +2 more
openaire   +4 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The effect of preoperative virtual reality on anxiety, pain and postoperative recovery in children undergoing circumcision

BMC Pediatrics
Background The present study aims to assess the anxiety and pain perception in children receiving virtual reality (VR) interventions before circumcision, as well as the impact of VR on postoperative recovery.
Lifeng Shen, Changying Mei, Hongxia Wang, Anni Xia, Tingting Fu, Hong Zhu   +5 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source