Results 41 to 50 of about 494,359 (316)

Survey the Effect of Virtual Network on the Knowledge and Clinical Skills of Surgical Technologist Students [PDF]

پیاورد سلامت, 2023
Background and Aim: Virtual networks have become one of the most influential tools in people’s lives, affecting various aspects of life. In medical sciences, with numerous advancements, the use of virtual networks is increasing. However, virtual networks
sedighe hannani, nazanin sarraf shahri, asma feizy dehkharghani, najme samii, azar arab khazaie, azin arab khazaie, kiarash kamboozia   +6 more
doaj  

Association between long working hours and mental health among nurses in China under COVID-19 pandemic: based on a large cross-sectional study

BMC Psychiatry, 2023
Objective Nurses were more likely to experience mental disorders due to long working hours and irregular schedules. However, studies addressing this issue are scarce; therefore, we aimed to investigate the association between long working hours and ...
Hongwei Che, Huiying Wu, Yu Qiao, Bonan Luan, Qingyun Zhao, Hongyan Wang   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Importance of the Return Air Opening to Degree of Turbulence in a I-Grade Clean Operating Room [PDF]

, 2006
In this paper, a high Reynold K-etwo equation model has been used. The range of return air openings that can be used has been induced by numerical simulation to influence the return air opening and degree of turbulence in an I-Grade clean operating room ...
Cheng, S.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Nurse-led discharge versus consulting surgeon-led discharge for patients who underwent laparoscopic surgeries: an evaluation of follow-up outcome, readmission frequencies, cost of care, and satisfaction of patients

BMC Nursing
Background Consulting surgeons review admitted patients and make decisions regarding their fitness for discharge. This leads to a delay in discharge. Delayed hospital discharge is an issue faced by patients after laparoscopic surgery, which increases ...
Bing Yang, Xiaotang Luo, Peiwei Wang, Pengfei Pan, Peishan Lin, Wenjie Zhao   +5 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Current status and factors associated with sexual harassment among operating room nurses: a multi-center cross-sectional study

BMC Nursing
Aims The purpose of this study was to investigate the prevalence of sexual harassment among operating room nurses, and to analyze the influencing factors.
Lingyu Tang, Xingli Yu, Yanshu Liu, Jie Zhou, Daiying Zhang, Juan Wang, Qingyan Liu   +6 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source