Results 41 to 50 of about 1,850,572 (305)
LINC01614 Promotes Colorectal Cancer Cell Growth and Migration by Regulating miR-217-5p/HMGA1 Axis
Analytical Cellular Pathology, 2023 Colorectal cancer (CRC) substantially contributes to cancer-related deaths worldwide. Recently, a long non-coding RNA (lncRNA), LINC01614, has emerged as a vital gene regulator in cancer progression.
Jiwei Jia +4 more
doaj +1 more source
Liquid cryogenic lubricant [PDF]
, 1970 Fluorinated polyethers are suitable lubricants for rolling-element bearings in cryogenic systems. Lubrication effectiveness is comparable to that of super-refined mineral oil lubricants operating at room ...
Dietrich, M. W. +2 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
BMC PediatricsBackground The present study aims to assess the anxiety and pain perception in children receiving virtual reality (VR) interventions before circumcision, as well as the impact of VR on postoperative recovery.
Lifeng Shen +5 more
doaj +1 more source
Improve Intra-Operative Nurse-to-Nurse Communication Using a Safety Checklist [PDF]
, 2015 Poor and inadequate handoff, or transfer of care of the surgical patient care from the primary to the relief operating room registered nurse circulators, can result in irreversible patient harm, or sentinel events, such as retained foreign items. In this
Rowe, Silvinita Tadeo
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Survey the Effect of Virtual Network on the Knowledge and Clinical Skills of Surgical Technologist Students [PDF]
پیاورد سلامت, 2023 Background and Aim: Virtual networks have become one of the most influential tools in people’s lives, affecting various aspects of life. In medical sciences, with numerous advancements, the use of virtual networks is increasing. However, virtual networks
sedighe hannani +6 more
doaj
Fatigue properties of sheet, bar, and cast metallic materials for cryogenic applications [PDF]
, 1970 Cryogenic fatigue and tensile properties for metallic materials are determined in the operating life-time range of ten thousand to ten million cycles at room temperature, at minus 320 degrees F, and at minus 423 degrees F. Results are presented as stress
Green, E. F.
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source