Results 121 to 130 of about 300,033 (304)

Influence of horizontal alignment elements on operating speed of vehicles on two-lane highways

Frontiers in Future Transportation
Earlier studies acknowledged that the design speed does not principally assure consistency in the design of highway geometric elements. Methodologies for estimating operating speeds are limited to specific or local traffic conditions and design standards,
Kiran Kumar Tottadi, Arpan Mehar
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The hyperbolic operators with the characteristics vanishing with the different speeds.

Osaka Journal of Mathematics, 2002
The authors investigate the Cauchy problem for operators with time-dependent coefficients: \[ P(t,D_t,D_x)=\sum_{j+|\alpha|\leq m} a_{j\alpha}(t)D^j_t D^\alpha_x,\;t\in[0,T],\;x\in\mathbb{R}^n. \] The roots \(\tau_j(t,x)\), \(j=1,\dots,m\), of the characteristic polynomial are assumed real-valued, satisfying the condition \(|\tau_j(t,\xi)-\tau_k (t,\xi)
Kajitani, Kunihiko, Wakabayashi, Seiichiro, Yagdjian, Karen   +2 more
openaire   +4 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Operating speed model for secondary road network [PDF]

, 2018
Model brzine ima široku primjenu u planiranju i projektiranju prometnica, a služi kako bi se u izabranom profilu prometne mreže što preciznije predvidjela brzina prolaza motornih vozila, koristeći pritom već poznate podatke o profilu koji se analizira.
Crnković, Ivana
core  

Pengaruh Lebar Lajur Lalu Lintas Terhadap Kecepatan Kendaraan Pada Jalan Perkotaan

Jurnal Bangunan, Konstruksi & Desain
The design of the road lane width plays an important role in controlling vehicle speed. Controlled vehicle speed will have an impact on traffic safety. The purpose of this study was to determine the effect of traffic lane width on average operating speed.
Titi Kurniati
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Experimental Verification of a Depth Controller using Model Predictive Control with Constraints onboard a Thruster Actuated AUV [PDF]

, 2012
In this work a depth and pitch controller for an autonomous underwater vehicle (AUV) is developed. This controller uses the model predictive control method to manoeuvre the vehicle whilst operating within the defined constraints of the AUV actuators ...
Rogers, E., Turnock, S.R., Steenson, Leo V., Phillips, A.B., Furlong, M.   +4 more
core  

Research on the Uplift Characteristics of Pantographs of High-Speed Trains Under Crosswind Conditions

Applied Sciences
Through the geometric relationships and force analysis of the main components of pantographs on high-speed trains, the coefficients of aerodynamic forces and lift transmission between the pantograph and main components under crosswind conditions were ...
Meng Zhao, Yaning Duan, Xingbo Lan, Zile Jia   +3 more
doaj   +1 more source