Results 61 to 70 of about 895,674 (297)
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
The structure of an operating system [PDF]
, 1976 This paper describes the use of the class and inner concepts of SIMULA 67 to express the multi-level structure of an operating system. A comparison is drawn between compile-time checking and run-time protection.
openaire +3 more sources
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
UNIX License Makes Linux the Last Major Piece of the Puzzle
Annals of Business Administrative Science, 2013 From 1992 to 1994, BSD which was UNIX developed at the University of California, Berkeley (UC Berkeley), found itself involved in a license-related lawsuit filed by AT&T. At around the same time, the GNU project, which developed a UNIX-like free software
Nobuo TAKAHASHI, Tomofumi TAKAMATSU
doaj +1 more source
Perancangan Aplikasi Voice Chat dengan Socket Programming pada Android untuk Jaringan Lokal
Jurnal Jaringan Telekomunikasi, 2020 Aplikasi voice chat merupakan aplikasi yang dirancang untuk menggantikan fungsi HT pada smartphone android. Selain dapat melakukan panggilan dengan suara, aplikasi ini juga dapat digunakan untuk melakukan komunikasi dengan text.
Allyza Nanda Purwari +2 more
doaj +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
ComputersSolid-state drives (SSDs) are widely adopted in mobile devices, desktop PCs, and data centers since they offer higher throughput, lower latency, and lower power consumption to modern computing systems and applications compared with hard disk drives (HDDs)
Inhwi Hwang +3 more
doaj +1 more source
, 2020 An Operating System is a program that acts as an intermediary between a user of a computer and the computer hardware. Objectives of Operating System are: Convenience: - for small PC’s. Efficiency: - for large, shared multi user systems since they are expensive.
openaire +2 more sources
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source